# SR-SPIDER POLYPEPTIDE-1

URL: https://app.greenveil.ai/ingredients/ingredient_inci_sr_spider_polypeptide_1
Categories: beauty
Functions: Hair conditioning, Nail conditioning, Skin protecting
Identifier: SR-SPIDER POLYPEPTIDE-1

> SR-SPIDER POLYPEPTIDE-1: Used in cosmetics as a hair conditioner, a nail conditioning agent and a skin protectant. Canonical ingredient record built from 1 public-source records. Compiled from 1 published data source.

## Safety assessment

- Chemical concern: not yet assessed
- Is it a concern? We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.
- Rationale: Canonical ingredient record built from 1 public-source records.

## Regulatory status

- EU: Active — sr-Spider Polypeptide-1 is a single chain recombinant spider protein, produced by fermentation in  E. coli.  The starting gene is a synthetically derived copy of the gene from  Araneus diadematus  which codes for Fibroin-4. The protein contains a maximum of 410 amino acids which may contain disulfide bonds and/or glycosylation, and consists of the proper sequence of the 20 standard amino acids.

## Expert safety opinions

- SCCS (EU Scientific Committee on Consumer Safety): no opinion on file.
- CIR (Cosmetic Ingredient Review (US expert panel)): no opinion on file.

## Data sources

- CosIng (updated 2026-09-23): https://ec.europa.eu/growth/tools-databases/cosing/details/92997

_Assessed by Greenveil._