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Stearyldisulfidehexyl SH-DNA-3 PEG-45/SH-RNA-2

Concern score

Not assessed — no hazard data yet.

Stearyldisulfidehexyl SH-DNA-3 PEG-45/SH-RNA-2 in plain language

What it does

Used in cosmetics as a hair conditioner.

  • Hair conditioning
Is it a concern?
We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

What we know about this ingredient

Canonical ingredient record built from 1 public-source records.

Regulation

No restrictions found. Stearyldisulfidehexyl SH-DNA-3 PEG-45/SH-RNA-2 appears in these published regulatory listings.

  • EUCosIngActiveStearyldisulfidehexyl sh-DNA-3 PEG-45/sh-RNA-2 is a synthetic human RNA strand conjugated with a synthetic human complementary DNA strand which is modified at the 5' end with Stearyldisulfidehexyl and at the 3' end with polyethylene glycol. The RNA is a Dickkopf-1-specific siRNA comprised of 19 ribonucleotides. The modified DNA is a complementary strand comprised of 19 deoxyribonucleotides selected from the human Dickkopf-1 mRNAs. This was developed for effective and specific degradation of mRNA coding for Dickkopf-1.
    • Stearyldisulfidehexyl sh-DNA-3 PEG-45/sh-RNA-2 is a synthetic human RNA strand conjugated with a synthetic human complementary DNA strand which is modified at the 5' end with Stearyldisulfidehexyl and at the 3' end with polyethylene glycol. The RNA is a Dickkopf-1-specific siRNA comprised of 19 ribonucleotides. The modified DNA is a complementary strand comprised of 19 deoxyribonucleotides selected from the human Dickkopf-1 mRNAs. This was developed for effective and specific degradation of mRNA coding for Dickkopf-1.Source →

Expert safety opinions

No expert opinion on file for Stearyldisulfidehexyl SH-DNA-3 PEG-45/SH-RNA-2. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Stearyldisulfidehexyl SH-DNA-3 PEG-45/SH-RNA-2 yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

1 data source

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.