# TETRAPEPTIDE-121

URL: https://app.greenveil.ai/ingredients/ingredient_inci_tetrapeptide_121
Categories: beauty
Functions: Emollient, Skin conditioning
Identifier: TETRAPEPTIDE-121

> TETRAPEPTIDE-121: Used in cosmetics as an emollient and a skin-conditioning agent. Canonical ingredient record built from 1 public-source records. Compiled from 1 published data source.

## Safety assessment

- Chemical concern: not yet assessed
- Is it a concern? We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.
- Rationale: Canonical ingredient record built from 1 public-source records.

## Regulatory status

- EU: Active — Tetrapeptide-121 is the synthetic peptide consisting of histidine, leucine, proline and threonine.

## Expert safety opinions

- SCCS (EU Scientific Committee on Consumer Safety): no opinion on file.
- CIR (Cosmetic Ingredient Review (US expert panel)): no opinion on file.

## Data sources

- CosIng (updated 2026-09-23): https://ec.europa.eu/growth/tools-databases/cosing/details/104709

_Assessed by Greenveil._