Skip to content
  • beauty
  • industrial

5-Nitro-o-toluidine [1]; 5-Nitro-o-toluidine hydrochloride [2]

CAS 99-55-8 · 100/100 · High conf.

5-Nitro-o-toluidine [1]; 5-Nitro-o-toluidine hydrochloride [2] chemical structure

Concern score

100/100Critical concern driven by cmr.
High confidence

5-Nitro-o-toluidine [1]; 5-Nitro-o-toluidine hydrochloride [2] in plain language

What it is

Also known as 5-NITRO-O-TOLUIDINE · 5-NITRO-ORTHO-TOLUIDINE · 2-METHYL-5-NITROANILINE · CI 37105 · 1-Amino-2-methyl-5-nitrobenzene · 2-AMINO-4-NITROTOLUENE

Show all 32 names

2-METHYL-5-NITRO-BENZENEAMINE · 2-Methyl-5-nitro-phenylamine · 2-Methyl-5-nitrobenzenamine · 3-NITRO-6-METHYLANILINE · 4-NITRO-2-AMINOTOLUENE · 5-NITRO-2-TOLUIDINE · 5-nitro-o-toluidine (sara 313) · 6-Methyl-3-nitroaniline · Amarthol Fast Scarlet G Base · Amarthol Fast Scarlet G salt · Benzenamine, 2-methyl-5-nitro- · Daito Scarlet Base G · Devol Scarlet B · Diabase Scarlet G · Fast Red SG Base · Fast Scarlet Base J · Fast Scarlet G · Fast Scarlet G Base · Fast scarlet base G · Naphtoelan fast scarlet g base · O-toluidine, 5-NITRO- · Pnot · Scarlet Base NSP · Scarlet G Base · Azoic diazo component 12 · C.I. azoic diazo component 12

What it does

We don't have a plain-language description for 5-Nitro-o-toluidine [1]; 5-Nitro-o-toluidine hydrochloride [2] yet.

Is it a concern?
Critical concern: classified for carcinogenic, mutagenic or reproductive toxicity (CMR). It is banned in EU cosmetics.

Why it's flagged

  • Cmr

5-Nitro-o-toluidine [1]; 5-Nitro-o-toluidine hydrochloride [2] is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.

RestrictedEU EC — banned

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

Restrictions first, then routine listings from published regulatory sources.

  • EU Annex II — prohibited
  • EU prohibited in cosmetics

Recorded in these product areas

  • Found in consumer products
  • Industrial
  • EUEC

    Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products. CMR: Carcinogenic Cat. 2()

    banned
    View source →
  • EUCosIngActiveCosmetics Regulation annex II / ref 1195.
    • Cosmetics Regulation annex II / ref 1195.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 4 composition records across product categories including Furniture and furnishings, Laboratory supplies.
    • EPA CPDat observed this chemical in 4 composition records across product categories including Furniture and furnishings, Laboratory supplies.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for 5-Nitro-o-toluidine [1]; 5-Nitro-o-toluidine hydrochloride [2]. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for 5-Nitro-o-toluidine [1]; 5-Nitro-o-toluidine hydrochloride [2] yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

7 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EU CosIng Cosmetics Regulation Annexes

    regulatory · updated 2016-11-24

    Open →
  • EPA Chemical and Products Database

    exposure · updated 2020-02-13

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often EPA CPDat has listed 5-Nitro-o-toluidine [1]; 5-Nitro-o-toluidine hydrochloride [2] in a product composition. These are source records, not Greenveil catalog products.

Source records

4

Named organisations

3

Furniture and furnishingsLaboratory supplies
See products using 5-Nitro-o-toluidine [1]; 5-Nitro-o-toluidine hydrochloride [2] →