Food use
Food-use source coverage is present in the current record.
The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.
- beauty
- industrial
4',5'-Dibromo-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one and its insoluble barium, strontium and zirconium lakes, salts and pigments
CAS 596-03-2 · 20/100 · High conf.
Also registered as 1 other CAS number
4372-02-5
Concern score
20/100Minor concern based on regulatory listings.
High confidence
4',5'-Dibromo-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one and its insoluble barium, strontium and zirconium lakes, salts and pigments in plain language
On cosmetic ingredient lists it appears as “CI 45370”.
Also known as CI 45370 · Solvent red 72
Used in cosmetics as a colourant and a hair dye. CI 45370 is classed chemically as a xanthene colour.
- Colorant
- Hair dyeing
- Colourant
- Minor concern: no hazard classifications on record. It is listed for cosmetic use in the EU.
What the listings say
Permitted, with conditions — 4',5'-Dibromo-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one and its insoluble barium, strontium and zirconium lakes, salts and pigments appears on published "allowed" regulatory lists rather than on a restriction list.
4',5'-Dibromo-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one and its insoluble barium, strontium and zirconium lakes, salts and pigments is listed in Annex IV of the EU Cosmetics Regulation (EC) 1223/2009 (colorants allowed in cosmetic products).
The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.
Regulation
No restrictions found. 4',5'-Dibromo-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one and its insoluble barium, strontium and zirconium lakes, salts and pigments appears in these published regulatory listings.
- EU Annex IV — permitted colorant
- EU permitted colorant
- Found in consumer products
- Industrial
EUCosIngActive3 entries
- CI 45370 is classed chemically as a xanthene colour. It conforms to the formula: Restriction: IV/75 (CI 45370) II/1333 (Solvent Red 72) and its disodium salt (CI 45370) when used as a substance in hair dye productsSource →
- Solvent Red 72 is classed chemically as a xanthene colour. It conforms to the formula: Restriction: II/1333 (when used as a substance in hair dye products)Source →
- Cosmetics Regulation annex IV / ref 75.Source →
EUECallowed_listedAnnex IV of EU Cosmetics Regulation (EC) 1223/2009: colorants allowed in cosmetic products. Conditions of use and warnings: Not more than 1% 2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid and 2% 2-(bromo-6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid
- Annex IV of EU Cosmetics Regulation (EC) 1223/2009: colorants allowed in cosmetic products. Conditions of use and warnings: Not more than 1% 2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid and 2% 2-(bromo-6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acidSource →
USEPAcommercial use observedEPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Dye.
- EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Dye.Source →
Expert safety opinions
No expert opinion on file for 4',5'-Dibromo-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one and its insoluble barium, strontium and zirconium lakes, salts and pigments. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.
SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.
Evidence & sources
No graded research studies for 4',5'-Dibromo-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one and its insoluble barium, strontium and zirconium lakes, salts and pigments yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.
Suitability
Context-specific fit derived from published classifications and the current ingredient evidence profile.
Good fit
Fragrance avoidance
No fragrance-linked caution surfaced in the current profile.
This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.
Where it has been recorded
How often EPA CPDat has listed 4',5'-Dibromo-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one and its insoluble barium, strontium and zirconium lakes, salts and pigments in a product composition. These are source records, not Greenveil catalog products.
Named organisations
2
Typical roles
ColorantHair dyeingColourant
Found in these products
Cosmetic and personal-care products that list 4',5'-Dibromo-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one and its insoluble barium, strontium and zirconium lakes, salts and pigments are shown first. Their ingredient lists include 4',5'-Dibromo-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one and its insoluble barium, strontium and zirconium lakes, salts and pigments; each product's own rating depends on its whole formula, so it is shown on the product page, not here.
