# 4',5'-Dibromo-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one; 4',5'-Dibromofluorescein; (Solvent Red 72) and its disodium salt (CI 45370) when used as a substance in hair dye products

URL: https://app.greenveil.ai/ingredients/ingredient_source_ref_annex_ref_ii_1333
Categories: beauty, industrial
Functions: colorant, Dye
Identifier: 596-03-2

> 4',5'-Dibromo-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one; 4',5'-Dibromofluorescein; (Solvent Red 72) and its disodium salt (CI 45370) when used as a substance in hair dye products is used as colorant / dye. Greenveil chemical-concern score: 100/100 — Critical concern based on regulatory listings.. Assessed from 3 sources.

## Safety assessment

- Chemical concern score: 100/100 — Critical concern based on regulatory listings.
- Confidence: 4
- Rationale: 4',5'-Dibromo-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one; 4',5'-Dibromofluorescein; (Solvent Red 72) and its disodium salt (CI 45370) when used as a substance in hair dye products is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.

## Regulatory status

- EU: banned — Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products.
- EU: allowed_listed — Annex IV of EU Cosmetics Regulation (EC) 1223/2009: colorants allowed in cosmetic products. Conditions of use and warnings: Not more than 1% 2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid and 2% 2-(bromo-6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid
- US: commercial use observed — EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Dye.

_Assessed by Greenveil._