# ESTRADIOL

URL: https://app.greenveil.ai/ingredients/ingredient_source_ref_annex_ref_ii_260
Categories: beauty, industrial
Functions: Softener and conditioner
Identifier: DTXSID0020573

> ESTRADIOL is used as softener and conditioner. Greenveil chemical-concern score: 100/100 — Critical concern based on regulatory listings.. Assessed from 6 sources.

## Safety assessment

- Chemical concern score: 100/100 — Critical concern based on regulatory listings.
- Confidence: 4
- Rationale: Oestrogens is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.

## Regulatory status

- EU: banned — Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products.
- US: commercial use observed — EPA CPDat observed this chemical in 7 composition records across product categories including Laboratory supplies, Personal care, Raw materials. EPA CPDat classifies this chemical for functional uses including Softener and conditioner.
- US: listed in openFDA substance — openFDA substance registry classifies this ingredient as chemical.

_Assessed by Greenveil._