# Hydroxy-8-quinoline and its sulphate bis(8-hydroxyquinolinium) sulphate, except for the uses of the  sulphate provided for in entry 51 of Annex III

URL: https://app.greenveil.ai/ingredients/ingredient_source_ref_substance_id_28741
Categories: beauty
Identifier: annex_ref:II:395

> Hydroxy-8-quinoline and its sulphate bis(8-hydroxyquinolinium) sulphate, except for the uses of the sulphate provided for in entry 51 of Annex III. Greenveil chemical-concern score: 100/100 — Critical concern driven by cmr.. Compiled from 2 published data sources.

## Safety assessment

- Chemical concern score: 100/100 — Critical concern driven by cmr.
- Confidence in this assessment: High
- Is it a concern? Critical concern: classified for carcinogenic, mutagenic or reproductive toxicity (CMR). It is banned in EU cosmetics.
- Rationale: Hydroxy-8-quinoline and its sulphate bis(8-hydroxyquinolinium) sulphate, except for the uses of the sulphate provided for in entry 51 of Annex III is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.

## Regulatory status

- EU: Active — Cosmetics Regulation annex II / ref 395.
- EU: banned — Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products. CMR: Reprotoxic Cat. 1B()

## Expert safety opinions

- SCCS (EU Scientific Committee on Consumer Safety): no opinion on file.
- CIR (Cosmetic Ingredient Review (US expert panel)): no opinion on file.

## Data sources

- CosIng (updated 2026-09-23): https://ec.europa.eu/growth/tools-databases/cosing/details/28741
- EU CosIng Cosmetics Regulation Annexes (updated 2020-07-31): https://ec.europa.eu/growth/tools-databases/cosing/reference/annexes/list/II

_Assessed by Greenveil._