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GREENVEIL

  • beauty

N-substituted derivatives of p- Phenylenediamine and their salts; N- substituted derivatives of o-Phenylenediamine (1 ), with exception of those derivatives listed elsewhere in this Annex and under reference numbers 1309, 1311, and 1312 in Annex II

70/100 · High conf.

Concern score

70/100High concern based on regulatory listings.
High confidence

N-substituted derivatives of p- Phenylenediamine and their salts; N- substituted derivatives of o-Phenylenediamine (1 ), with exception of those derivatives listed elsewhere in this Annex and under reference numbers 1309, 1311, and 1312 in Annex II in plain language

What it is

On cosmetic ingredient lists it appears as “N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE sulfate”.

Also known as N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE sulfate · N-phenyl-p-phenylenediamine · N-phenyl-p-phenylenediamine hcl · N-phenyl-p-phenylenediamine sulfate

What it does

We don't have a plain-language description for N-substituted derivatives of p- Phenylenediamine and their salts; N- substituted derivatives of o-Phenylenediamine (1 ), with exception of those derivatives listed elsewhere in this Annex and under reference numbers 1309, 1311, and 1312 in Annex II yet.

Is it a concern?
High concern: no hazard classifications on record. It is restricted in EU cosmetics.

Why it's flagged

N-substituted derivatives of p- Phenylenediamine and their salts; N- substituted derivatives of o-Phenylenediamine (1 ), with exception of those derivatives listed elsewhere in this Annex and under reference numbers 1309, 1311, and 1312 in Annex II is restricted in cosmetic products under Annex III of the EU Cosmetics Regulation (EC) 1223/2009.

RestrictedEU EC — restricted

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

Restrictions first, then routine listings from published regulatory sources.

  • EU Annex III — restricted
  • EU restricted in cosmetics

  • EUEC

    Annex III of EU Cosmetics Regulation (EC) 1223/2009: substances which cosmetic products must not contain except subject to the restrictions laid down. Product types: Hair dye substance in oxidative hair dye products Maximum concentration: (a) General use (b) Professional use For (a) and (b): After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 3 % calculated as free base Other conditions: (1 ) These substances may be used singly or in combination provided that the sum of the ratios of the levels of each of them in the cosmetic product expressed with reference to the maximum level authorised for each of them does not exceed 1.’ Conditions of use and warnings: (a) To be printed on the label: The mixing ratio. “ Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever…

    restricted
    View source →
  • EUCosIngActiveCosmetics Regulation annex III / ref 8.

Expert safety opinions

No expert opinion on file for N-substituted derivatives of p- Phenylenediamine and their salts; N- substituted derivatives of o-Phenylenediamine (1 ), with exception of those derivatives listed elsewhere in this Annex and under reference numbers 1309, 1311, and 1312 in Annex II. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for N-substituted derivatives of p- Phenylenediamine and their salts; N- substituted derivatives of o-Phenylenediamine (1 ), with exception of those derivatives listed elsewhere in this Annex and under reference numbers 1309, 1311, and 1312 in Annex II yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

2 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →

  • EU CosIng Cosmetics Regulation Annexes

    regulatory · updated 2014-06-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Catalog

Found in these products

Their ingredient lists include N-substituted derivatives of p- Phenylenediamine and their salts; N- substituted derivatives of o-Phenylenediamine (1 ), with exception of those derivatives listed elsewhere in this Annex and under reference numbers 1309, 1311, and 1312 in Annex II; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

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