# N-substituted derivatives of p- Phenylenediamine and their salts; N- substituted derivatives of o-Phenylenediamine (1 ), with exception of those derivatives listed elsewhere in this Annex and under reference numbers 1309, 1311, and 1312 in Annex II

URL: https://app.greenveil.ai/ingredients/ingredient_source_ref_substance_id_87594
Categories: beauty
Identifier: annex_ref:III:8

> N-substituted derivatives of p- Phenylenediamine and their salts; N- substituted derivatives of o-Phenylenediamine (1 ), with exception of those derivatives listed elsewhere in this Annex and under reference numbers 1309, 1311, and 1312 in Annex II. Greenveil chemical-concern score: 70/100 — High concern based on regulatory listings.. Compiled from 2 published data sources.

## Safety assessment

- Chemical concern score: 70/100 — High concern based on regulatory listings.
- Confidence in this assessment: High
- Is it a concern? High concern: no hazard classifications on record. It is restricted in EU cosmetics.
- Rationale: N-substituted derivatives of p- Phenylenediamine and their salts; N- substituted derivatives of o-Phenylenediamine (1 ), with exception of those derivatives listed elsewhere in this Annex and under reference numbers 1309, 1311, and 1312 in Annex II is restricted in cosmetic products under Annex III of the EU Cosmetics Regulation (EC) 1223/2009.

## Regulatory status

- EU: Active — Cosmetics Regulation annex III / ref 8.
- EU: restricted — Annex III of EU Cosmetics Regulation (EC) 1223/2009: substances which cosmetic products must not contain except subject to the restrictions laid down. Product types: Hair dye substance in oxidative hair dye products Maximum concentration: (a) General use (b) Professional use For (a) and (b): After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 3 % calculated as free base Other conditions: (1 ) These substances may be used singly or in combination provided that the sum of the ratios of the levels of each of them in the cosmetic product expressed with reference to the maximum level authorised for each of them does not exceed 1.’ Conditions of use and warnings: (a) To be printed on the label: The mixing ratio. “ Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever…

## Expert safety opinions

- SCCS (EU Scientific Committee on Consumer Safety): no opinion on file.
- CIR (Cosmetic Ingredient Review (US expert panel)): no opinion on file.

## Data sources

- CosIng (updated 2026-09-23): https://ec.europa.eu/growth/tools-databases/cosing/details/87594
- EU CosIng Cosmetics Regulation Annexes (updated 2014-06-17): https://ec.europa.eu/growth/tools-databases/cosing/reference/annexes/list/III

_Assessed by Greenveil._