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Cells, tissues or products of human origin

CAS 148294-77-3 · 100/100 · High conf.

Also registered as 1 other CAS number

928858-36-0

Concern score

100/100Critical concern based on regulatory listings.
High confidence

Cells, tissues or products of human origin in plain language

What it is

On cosmetic ingredient lists it appears as “RH-POLYPEPTIDE-1”.

Also known as RH-POLYPEPTIDE-1 · RH-POLYPEPTIDE-13 · RH-POLYPEPTIDE-14 · RH-POLYPEPTIDE-16 · RH-POLYPEPTIDE-2 · RH-POLYPEPTIDE-27

Show all 18 names

RH-POLYPEPTIDE-3 · RH-POLYPEPTIDE-4 · RH-POLYPEPTIDE-5 · RH-POLYPEPTIDE-6 · RH-POLYPEPTIDE-7 · RH-POLYPEPTIDE-8 · Human noggin · SH-POLYPEPTIDE-13 · Human OLIGOPEPTIDE-18 · Noggin · Noggin (human) · Nexpure bio noggin

What it does

We don't have a plain-language description for Cells, tissues or products of human origin yet.

Is it a concern?
Critical concern: no hazard classifications on record. It is banned in EU cosmetics.

Why it's flagged

Cells, tissues or products of human origin is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.

RestrictedEU EC — banned

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

Restrictions first, then routine listings from published regulatory sources.

  • EU Annex II — prohibited
  • EU prohibited in cosmetics
  • EUEC

    Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products.

    banned
    View source →
  • EUCosIngActiveCosmetics Regulation annex II / ref 416.
    • Cosmetics Regulation annex II / ref 416.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as protein.
    • openFDA substance registry classifies this ingredient as protein.Source →

Expert safety opinions

No expert opinion on file for Cells, tissues or products of human origin. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Cells, tissues or products of human origin yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

4 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EU CosIng Cosmetics Regulation Annexes

    regulatory · updated 2023-01-20

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.