# ACETYL HEXAPEPTIDE-49

URL: https://app.greenveil.ai/ingredients/ingredient_unii_4055_x1_s509
Categories: beauty
Functions: Skin conditioning
Identifier: ACETYL HEXAPEPTIDE-49

> ACETYL HEXAPEPTIDE-49: Used in cosmetics as a skin-conditioning agent. FDA GSRS classifies this ingredient as ingredient substance chemical. Compiled from 4 published data sources.

## Safety assessment

- Chemical concern: not yet assessed
- Is it a concern? We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.
- Rationale: FDA GSRS classifies this ingredient as ingredient substance chemical.

## Regulatory status

- EU: Active — Acetyl Hexapeptide-49 is the product obtained by the acetylation of Hexapeptide-49.
- US: listed in openFDA substance — openFDA substance registry classifies this ingredient as concept.

## Expert safety opinions

- SCCS (EU Scientific Committee on Consumer Safety): no opinion on file.
- CIR (Cosmetic Ingredient Review (US expert panel)): no opinion on file.

## Data sources

- CosIng (updated 2026-09-23): https://ec.europa.eu/growth/tools-databases/cosing/details/90869
- FDA GSRS UNII (updated 2026-02-26): https://precision.fda.gov/uniisearch/
- openFDA Substance (updated 2026-05-24): https://api.fda.gov/other/substance.json?search=unii:4055X1S509
- PubChem Live Enrichment (updated 2026-05-17): https://pubchem.ncbi.nlm.nih.gov/compound/162625096

_Assessed by Greenveil._