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Ceramide 5

CAS 100403-19-8

Also registered as 2 other CAS numbers

111122-59-9 · 288072-63-9

Ceramide 5 chemical structure

Concern score

Not assessed — no hazard data yet.

Ceramide 5 in plain language

What it is

Also known as Ceramide 5 (retired) · Ceramide as (ceramide 5) · 2-OH-C24 :0 Ceramide · Cer(d18:1/24:0(2OH)) · N-(2-hydroxytetracosanoyl)-4-sphingenine · N-2-cerabronoylsphingosine

Show all 11 names

N-2-hydroxylignoceroylsphingosine · N-2-hydroxytetracosanoyl ceramide · N-2-hydroxytetracosanoylsphingosine · TIC-006 · UNII-7848GX36YB

What it does

Used in cosmetics as a skin-conditioning agent and a hair conditioner. Ceramide 5 (Retired) is the N-acylated sphingolipid having the erythro structure.

  • Skin conditioning
  • Hair conditioning
Is it a concern?
We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

What we know about this ingredient

FDA GSRS classifies this ingredient as ingredient substance chemical.

Regulation

No restrictions found. Ceramide 5 appears in these published regulatory listings.

  • EUCosIngActiveCeramide 5 (Retired) is the N-acylated sphingolipid having the erythro structure that conforms generally to the formula, where m has a value ranging from 13 to 27 in which the acyl moiety may be saturated or mono-unsatuarated and n has a value ranging from 10 to 16. Ceramide 5 is similar to Ceramide 4, however, the acylating hydroxy acids are generally longer in Ceramide 5 than in Ceramide 4. The INCI Name, Ceramide 5, originally developed in 1997, was designated with a retired status in 2014. For an interim period of time, trade name assignments formerly published with the INCI Name Ceramide 5 will be retained in the retired monograph, and also published with the new name assignment, Ceramide AS.
    • Ceramide 5 (Retired) is the N-acylated sphingolipid having the erythro structure that conforms generally to the formula, where m has a value ranging from 13 to 27 in which the acyl moiety may be saturated or mono-unsatuarated and n has a value ranging from 10 to 16. Ceramide 5 is similar to Ceramide 4, however, the acylating hydroxy acids are generally longer in Ceramide 5 than in Ceramide 4. The INCI Name, Ceramide 5, originally developed in 1997, was designated with a retired status in 2014. For an interim period of time, trade name assignments formerly published with the INCI Name Ceramide 5 will be retained in the retired monograph, and also published with the new name assignment, Ceramide AS.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Ceramide 5. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Ceramide 5 yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

4 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.