# CERAMIDE 5

URL: https://app.greenveil.ai/ingredients/ingredient_unii_7848_gx36_yb
Categories: beauty
Functions: Skin conditioning, Hair conditioning
Identifier: CERAMIDE 5

> CERAMIDE 5: Used in cosmetics as a skin-conditioning agent and a hair conditioner. Ceramide 5 (Retired) is the N-acylated sphingolipid having the erythro structure. FDA GSRS classifies this ingredient as ingredient substance chemical. Compiled from 4 published data sources.

## Safety assessment

- Chemical concern: not yet assessed
- Is it a concern? We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.
- Rationale: FDA GSRS classifies this ingredient as ingredient substance chemical.

## Regulatory status

- EU: Active — Ceramide 5 (Retired) is the N-acylated sphingolipid having the erythro structure that conforms generally to the formula, where m has a value ranging from 13 to 27 in which the acyl moiety may be saturated or mono-unsatuarated and n has a value ranging from 10 to 16. Ceramide 5 is similar to Ceramide 4, however, the acylating hydroxy acids are generally longer in Ceramide 5 than in Ceramide 4.

The INCI Name, Ceramide 5, originally developed in 1997, was designated with a retired status in 2014. For an interim period of time, trade name assignments formerly published with the INCI Name Ceramide 5 will be retained in the retired monograph, and also published with the new name assignment, Ceramide AS.
- US: listed in openFDA substance — openFDA substance registry classifies this ingredient as chemical.

## Expert safety opinions

- SCCS (EU Scientific Committee on Consumer Safety): no opinion on file.
- CIR (Cosmetic Ingredient Review (US expert panel)): no opinion on file.

## Data sources

- CosIng (updated 2026-09-23): https://ec.europa.eu/growth/tools-databases/cosing/details/96265
- FDA GSRS UNII (updated 2026-02-26): https://precision.fda.gov/uniisearch/
- openFDA Substance (updated 2026-05-24): https://api.fda.gov/other/substance.json?search=unii:7848GX36YB
- PubChem Live Enrichment (updated 2026-05-17): https://pubchem.ncbi.nlm.nih.gov/compound/72715765

_Assessed by Greenveil._