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SH-DECAPEPTIDE-23

CAS 9041-90-1

Also registered as 2 other CAS numbers

28521-46-2 · 484-42-4

SH-DECAPEPTIDE-23 chemical structure

Concern score

Not assessed — no hazard data yet.

SH-DECAPEPTIDE-23 in plain language

What it is

Also known as Angiotensin i · Angiotensin i (human) · Angiotensin i (mouse) · Angiotensin i (rat) · Angiotensin i 5-ISOLEUCINE · Angiotensin i, 5-L-ISOLEUCINE-

Show all 17 names

Asp-arg-val-tyr-ile-his-pro-phe-his-leu · Human angiotensin i · 5-Ile-angiotensin I · Angiotensin 1, Human · Angiotensin I (human, mouse, rat) · Angiotensin I, ile(5)- · Angiotensins; Angiotonin · Bf-angiotensin 1 · C62H89N17O14 · Pepsitensin · Proangiotensin

What it does

Used in cosmetics as an antioxidant and a skin protectant.

  • Antioxidant
  • Skin protecting
Is it a concern?
We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

What we know about this ingredient

FDA GSRS classifies this ingredient as ingredient substance protein.

Regulation

No restrictions found. SH-DECAPEPTIDE-23 appears in these published regulatory listings.

  • EUCosIngActivesh-Decapeptide-23 is a single chain human peptide produced synthetically to be identical to a portion of the protein, Angiotensinogen (AGT) and contains 10 amino acids consisting of arginine, aspartic acid, histidine, isoleucine, leucine, phenylalanine, proline, tyrosine and valine.
    • sh-Decapeptide-23 is a single chain human peptide produced synthetically to be identical to a portion of the protein, Angiotensinogen (AGT) and contains 10 amino acids consisting of arginine, aspartic acid, histidine, isoleucine, leucine, phenylalanine, proline, tyrosine and valine.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as protein.
    • openFDA substance registry classifies this ingredient as protein.Source →

Expert safety opinions

No expert opinion on file for SH-DECAPEPTIDE-23. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for SH-DECAPEPTIDE-23 yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

4 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.