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Dynorphin a

CAS 74913-18-1

Also registered as 1 other CAS number

80448-90-4

Dynorphin a chemical structure

Concern score

Not assessed — no hazard data yet.

Dynorphin a in plain language

What it is

On cosmetic ingredient lists it appears as “SH-OLIGOPEPTIDE-71”.

Also known as SH-OLIGOPEPTIDE-71 · Dynorphin · Dynorphin A (swine) · DYN-A17 · Dynorphin a (1-17) · Dynorphin a (bos taurus)

Show all 20 names

Dynorphin a (human) · Dynorphin a (pig) · Dynorphin a (porcine) · Dynorphin a (rat) · Dynorphins · Porcine dynorphin a (1-17) · Dyn A 1-17 · Dynorphin 17 · porcine Dynorphin A amide · Dynorphin A trifluoroacetate salt · Dynorphin A1-17 · H-yggflrrirpklkwdnq-oh · Jmnjygmaumannw-fixztsjvsa-n · UNII-9M18T0TD14

What it does

Used in cosmetics as an anti-sebum and a skin protectant.

  • Anti-sebum
  • Skin protecting
Is it a concern?
We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

What we know about this ingredient

FDA GSRS classifies this ingredient as ingredient substance chemical.

Regulation

No restrictions found. Dynorphin a appears in these published regulatory listings.

  • EUCosIngActivesh-Oligopeptide-71 is a single chain recombinant human peptide produced by fermentation in E. coli. The starting gene is a synthesized copy of the human gene which codes for Dynorphin used as such or adapted to the production host. It contains a maximum of 254 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids.
    • sh-Oligopeptide-71 is a single chain recombinant human peptide produced by fermentation in E. coli. The starting gene is a synthesized copy of the human gene which codes for Dynorphin used as such or adapted to the production host. It contains a maximum of 254 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Dynorphin a. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Dynorphin a yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

4 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.