# DYNORPHIN A

URL: https://app.greenveil.ai/ingredients/ingredient_unii_9_m18_t0_td14
Categories: beauty
Functions: Anti-sebum, Skin protecting
Identifier: SH-OLIGOPEPTIDE-71

> DYNORPHIN A: Used in cosmetics as an anti-sebum and a skin protectant. FDA GSRS classifies this ingredient as ingredient substance chemical. Compiled from 4 published data sources.

## Safety assessment

- Chemical concern: not yet assessed
- Is it a concern? We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.
- Rationale: FDA GSRS classifies this ingredient as ingredient substance chemical.

## Regulatory status

- EU: Active — sh-Oligopeptide-71 is a single chain recombinant human peptide produced by fermentation in E. coli. The starting gene is a synthesized copy of the human gene which codes for Dynorphin used as such or adapted to the production host. It contains a maximum of 254 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids.
- US: listed in openFDA substance — openFDA substance registry classifies this ingredient as chemical.

## Expert safety opinions

- SCCS (EU Scientific Committee on Consumer Safety): no opinion on file.
- CIR (Cosmetic Ingredient Review (US expert panel)): no opinion on file.

## Data sources

- CosIng (updated 2026-09-23): https://ec.europa.eu/growth/tools-databases/cosing/details/88997
- FDA GSRS UNII (updated 2026-02-26): https://precision.fda.gov/uniisearch/
- openFDA Substance (updated 2026-05-24): https://api.fda.gov/other/substance.json?search=unii:9M18T0TD14
- PubChem Live Enrichment (updated 2026-05-17): https://pubchem.ncbi.nlm.nih.gov/compound/16133805

_Assessed by Greenveil._