Fragrance avoidance
No fragrance-linked caution surfaced in the current profile.
This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.
FDA NDC lists this ingredient in 7 active drug products and 7 total products.
Concern score
The concern value is driven by the published classifications and regulatory status below — not by a single signal.
Concern score 45/100 (moderate) · high confidence.
Prevalence of APPLE in our catalog (fda_ndc).
Products
7
Context-specific fit derived from published classifications and the current ingredient evidence profile.
Fragrance avoidance
No fragrance-linked caution surfaced in the current profile.
This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.
The published evidence profile currently shaping this ingredient record.
Primary documents currently linked to this ingredient record.
Structured claim signals pulled from linked ingredient research.
Published jurisdiction-level classifications and regulatory designations for this ingredient.
US
FDA
FDA NDC lists this ingredient in 7 active drug products and 7 total products.
US
FDA
openFDA substance registry classifies this ingredient as structurallydiverse.