Skip to content
  • beauty
  • industrial

SH-POLYPEPTIDE-61

CAS 1637217-80-1

Concern score

Not assessed — no hazard data yet.

SH-POLYPEPTIDE-61 in plain language

What it is

Also known as MITSUGUMIN-53 · MG53 · Recombinant human MG53 protein · TRIM72 expressed protein · Tripartite motif-containing protein 72

What it does

Used in cosmetics as a skin-conditioning agent, an astringent and a skin protectant.

  • Skin conditioning
  • Astringent
  • Skin protecting
  • Humectant
  • Conditioner
Is it a concern?
We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

Regulation

No restrictions found. SH-POLYPEPTIDE-61 appears in these published regulatory listings.

Recorded in these product areas

  • Found in consumer products
  • Industrial
  • EUCosIngActivesh-Polypeptide-61 is a synthetic peptide chemically produced to be identical to the human protein or piece of human protein, Tripartite Motif-Containing Protein 72. It contains a maximum of 477 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids.
    • sh-Polypeptide-61 is a synthetic peptide chemically produced to be identical to the human protein or piece of human protein, Tripartite Motif-Containing Protein 72. It contains a maximum of 477 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Humectant, Astringent, Softener and conditioner.
    • EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Humectant, Astringent, Softener and conditioner.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as protein.
    • openFDA substance registry classifies this ingredient as protein.Source →

Expert safety opinions

No expert opinion on file for SH-POLYPEPTIDE-61. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for SH-POLYPEPTIDE-61 yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

4 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EPA Chemical and Products Database

    exposure · updated 2019-12-20

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
Reference links (1)

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.

Where it has been recorded

How often EPA CPDat has listed SH-POLYPEPTIDE-61 in a product composition. These are source records, not Greenveil catalog products.

Named organisations

1

Typical roles

Skin conditioningAstringentSkin protectingHumectantConditioner
See products using SH-POLYPEPTIDE-61 →