Ingredients pharma Poloxamer 188 Poloxamer 188 CAS 691397-13-4
Concern score
Not assessed — no hazard data yet.
Why it's flagged Route: INTRAMUSCULAR; Dosage form: INJECTION, POWDER, FOR SUSPENSION; Maximum daily exposure: 4 mg
Regulation No restrictions found. Poloxamer 188 appears in these published regulatory listings.
definition_level:incomplete definition_type:primary inactive_ingredient_database ingredient_type:ingredient substance substance_class:polymer substance_type:polymer US FDA inactive ingredient database 22 entries — 6 administration routes Route: INTRAMUSCULAR; Dosage form: INJECTION, POWDER, FOR SUSPENSION; Maximum daily exposure: 4 mg Source → Route: INTRAMUSCULAR; Dosage form: POWDER, FOR SUSPENSION; Potency: 0.2 %w/v Source → Route: INTRAVENOUS; Dosage form: INJECTION; Potency: 6 mg Source → Route: INTRAVENOUS; Dosage form: INJECTION, POWDER, FOR SOLUTION; Potency: 2.2 mg Source → Route: OPHTHALMIC; Dosage form: SOLUTION; Potency: 0.1 %w/v Source → Route: ORAL; Dosage form: CAPSULE; Maximum daily exposure: 151 mg Source → Route: ORAL; Dosage form: CAPSULE, DELAYED RELEASE; Maximum daily exposure: 18 mg Source → Route: ORAL; Dosage form: CONCENTRATE; Maximum daily exposure: 3 mg Source → Route: ORAL; Dosage form: GRANULE; Maximum daily exposure: 81 mg Source → Route: ORAL; Dosage form: GRANULE, FOR SOLUTION; Maximum daily exposure: 624 mg Source → Route: ORAL; Dosage form: POWDER, FOR SOLUTION; Maximum daily exposure: 500 mg Source → Route: ORAL; Dosage form: POWDER, FOR SUSPENSION; Maximum daily exposure: 30 mg Source → Route: ORAL; Dosage form: SOLUTION; Maximum daily exposure: 1800 mg Source → Route: ORAL; Dosage form: SUSPENSION; Maximum daily exposure: 1600 mg Source → Route: ORAL; Dosage form: SUSPENSION, EXTENDED RELEASE; Maximum daily exposure: 6 mg Source → Route: ORAL; Dosage form: TABLET; Maximum daily exposure: 100 mg Source → Route: ORAL; Dosage form: TABLET, COATED; Potency: 3 mg Source → Route: ORAL; Dosage form: TABLET, DELAYED RELEASE; Maximum daily exposure: 6 mg Source → Route: ORAL; Dosage form: TABLET, EXTENDED RELEASE; Maximum daily exposure: 37 mg Source → Route: ORAL; Dosage form: TABLET, FILM COATED; Maximum daily exposure: 3 mg Source → Route: PERIODONTAL; Dosage form: GEL; Potency: 55 mg Source → Route: TOPICAL; Dosage form: CREAM; Potency: 1 %w/w Source → US FDA listed in openFDA substance openFDA substance registry classifies this ingredient as polymer. openFDA substance registry classifies this ingredient as polymer. Source → Evidence No graded sources yet for Poloxamer 188. We publish evidence only once a source is linked and reviewed — this ingredient is in the catalog, but has not been assessed.
Suitability Context-specific fit derived from published classifications and the current ingredient evidence profile.
Fragrance avoidance
No fragrance-linked caution surfaced in the current profile.
Good fitThis ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.
Catalog
Found in these products 9 products