- beauty
Proteinase-activated receptor 2
Concern score
Not assessed — no hazard data yet.
Proteinase-activated receptor 2 in plain language
On cosmetic ingredient lists it appears as “SH-HEXAPEPTIDE-6 sp amide”.
Also known as SH-HEXAPEPTIDE-6 sp amide · Coagulation factor ii receptor-like 1 · G-protein coupled receptor 11 · GPR11 · PAR-2 · PAR2
Show all 7 names
Thrombin receptor-like 1
Used in cosmetics as an antioxidant.
- Antioxidant
- We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.
What we know about this ingredient
FDA GSRS classifies this ingredient as ingredient substance protein.
Regulation
No restrictions found. Proteinase-activated receptor 2 appears in these published regulatory listings.
EUCosIngActivesh-Hexapeptide-6 SP Amide is a single chain human peptide, produced synthetically to be identical to a portion of the protein Proteinase-Activated Receptor 2, and contains 6 amino acids consisting of glycine, isoleucine, leucine, lysine, serine, and valine, in which the C-terminus is an amide.
- sh-Hexapeptide-6 SP Amide is a single chain human peptide, produced synthetically to be identical to a portion of the protein Proteinase-Activated Receptor 2, and contains 6 amino acids consisting of glycine, isoleucine, leucine, lysine, serine, and valine, in which the C-terminus is an amide.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as protein.
- openFDA substance registry classifies this ingredient as protein.Source →
Expert safety opinions
No expert opinion on file for Proteinase-activated receptor 2. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.
SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.
Evidence & sources
No graded research studies for Proteinase-activated receptor 2 yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.
Where this comes from
Reference links (1)
Suitability
Context-specific fit derived from published classifications and the current ingredient evidence profile.
Fragrance avoidance
Nothing to weigh for this context yet.
We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.