# alpha-Vitamin E

URL: https://app.greenveil.ai/ingredients/ingredient_dtxsid_dtxsid0026339
Categories: beauty, cleaning, food, industrial, pharma
Functions: Antioxidant, Occlusive, Skin conditioning, Fragrance, Preservative, Conditioner
Identifier: DTXSID0026339

> alpha-Vitamin E: Used in cosmetics as an antioxidant, an occlusive and a skin-conditioning agent. Tocopherol consists of alpha-tocopherol, beta-tocopherol, delta-tocopherol and/or gamma-tocopherol. Greenveil chemical-concern score: 40/100 — Moderate concern based on regulatory listings.. Compiled from 8 published data sources.

## Safety assessment

- Chemical concern score: 40/100 — Moderate concern based on regulatory listings.
- Confidence in this assessment: High
- Is it a concern? Moderate concern: no hazard classifications on record. It is listed for cosmetic use in the EU.
- Rationale: EPA CPDat observed this chemical in 33 composition records across product categories including Industrial products, Laboratory supplies, Personal care.

## Regulatory status

- EU: Active — Tocopherol consists of alpha-tocopherol, beta-tocopherol, delta-tocopherol and/or gamma-tocopherol and conforms to the formulae:
- EU: Report from international authority — Opinion of the Scientific Committee on Food on the Tolerable Upper Intake Level of Vitamin E (SCF)
- EU: EFSA opinion — Assessment of a feed additive consisting of RRR-alphatocopheryl acetate (vitamin E) for all animal species for the renewal of its authorisation (Specialty Ingredients (Europe) B.V. and Vitae Caps S.A.) (EFSA FEEDAP)
- EU: EFSA opinion — Assessment of a feed additive consisting of all-rac-alpha tocopheryl acetate (vitamin E) for all animal species for the renewal of its authorisation (EUROPE-ASIA Import Export GmbH) (EFSA FEEDAP)
- EU: EFSA opinion — Assessment of a feed additive consisting of all-rac-alpha tocopheryl acetate (vitamin E) for all animal species for the renewal of its authorisation (DSM) (EFSA FEEDAP)
- EU: EFSA opinion — Assessment of a feed additive consisting of all-rac-alphatocopheryl acetate (vitamin E) for all animal species for the renewal of its authorisation (NHU Europe GmbH) (EFSA FEEDAP)
- EU: EFSA opinion — Opinion on mixed tocopherols, tocotrienol tocopherol and tocotrienols as sources for vitamin E added as a nutritional substance in food supplements - Scientific Opinion of the Panel on Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (EFSA AFC)
- EU: EFSA opinion — Scientific Opinion on the safety and efficacy of vitamin E as a feed additive for all animal species (EFSA FEEDAP)
- EU: EFSA opinion — Assessment of a feed additive consisting of all-rac-alpha tocopheryl acetate (vitamin E) for all animal species for the renewal of its authorisation (BASF SE) (EFSA FEEDAP)
- GLOBAL: 0-2 mg/kg bw — JECFA evaluation lists ADI 0-2 mg/kg bw. Functional class: antioxidant.
- GLOBAL: Evaluated — JECFA evaluation record.
- GLOBAL: Evaluated — JECFA evaluation record. Functional class: antioxidant.
- US: commercial use observed — EPA CPDat observed this chemical in 33 composition records across product categories including Industrial products, Laboratory supplies, Personal care. EPA CPDat classifies this chemical for functional uses including Softener and conditioner, Binder, Fragrance.
- US: listed in openFDA substance — openFDA substance registry classifies this ingredient as chemical.

## Expert safety opinions

- SCCS (EU Scientific Committee on Consumer Safety): no opinion on file.
- CIR (Cosmetic Ingredient Review (US expert panel)): no opinion on file.
- EFSA (European Food Safety Authority): Opinion of the Scientific Committee on Food on the Tolerable Upper Intake Level of Vitamin E (SCF) — 2003 — http://dx.doi.org/s://ec.europa.eu/food/sites/food/files/safety/docs/sci-com_scf_out195_en.pdf; Assessment of a feed additive consisting of RRR-alphatocopheryl acetate (vitamin E) for all animal species for the renewal of its authorisation (Specialty Ingredients (Europe) B.V. and Vitae Caps S.A.) (EFSA FEEDAP) — 2021 — https://doi.org/10.2903/j.efsa.2021.6532; Assessment of a feed additive consisting of all-rac-alpha tocopheryl acetate (vitamin E) for all animal species for the renewal of its authorisation (EUROPE-ASIA Import Export GmbH) (EFSA FEEDAP) — 2021 — https://doi.org/10.2903/j.efsa.2021.6530; Assessment of a feed additive consisting of all-rac-alpha tocopheryl acetate (vitamin E) for all animal species for the renewal of its authorisation (DSM) (EFSA FEEDAP) — 2021 — https://doi.org/10.2903/j.efsa.2021.6529; Assessment of a feed additive consisting of all-rac-alphatocopheryl acetate (vitamin E) for all animal species for the renewal of its authorisation (NHU Europe GmbH) (EFSA FEEDAP) — 2021 — https://doi.org/10.2903/j.efsa.2021.6533; Opinion on mixed tocopherols, tocotrienol tocopherol and tocotrienols as sources for vitamin E added as a nutritional substance in food supplements - Scientific Opinion of the Panel on Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (EFSA AFC) — 2008 — https://doi.org/10.2903/j.efsa.2008.640; Scientific Opinion on the safety and efficacy of vitamin E as a feed additive for all animal species (EFSA FEEDAP) — 2010 — https://doi.org/10.2903/j.efsa.2010.1635; Assessment of a feed additive consisting of all-rac-alpha tocopheryl acetate (vitamin E) for all animal species for the renewal of its authorisation (BASF SE) (EFSA FEEDAP) — 2021 — https://doi.org/10.2903/j.efsa.2021.6531.
- JECFA (Joint FAO/WHO Expert Committee on Food Additives): JECFA evaluation lists ADI 0-2 mg/kg bw. Functional class: antioxidant. — https://apps.who.int/food-additives-contaminants-jecfa-database/Home/Chemical/3027; JECFA evaluation record. — https://apps.who.int/food-additives-contaminants-jecfa-database/Home/Chemical/3026; JECFA evaluation record. Functional class: antioxidant. — https://apps.who.int/food-additives-contaminants-jecfa-database/Home/Chemical/4871.

## Data sources

- CosIng (updated 2026-09-23): https://ec.europa.eu/growth/tools-databases/cosing/details/80273
- EFSA OpenFoodTox (updated 2026-10-04): https://doi.org/10.5281/zenodo.8120114
- EPA Chemical and Products Database (updated may 30, 2017): http://siri.org/msds/f2/bxz/bxzrf.html
- EPA DSSTox Identifiers (updated 2025-12-29): https://epa.figshare.com/articles/dataset/Chemistry_Dashboard_Data_DSSTox_Identifiers_Mapped_to_CAS_Numbers_and_Names/5588566
- FDA GSRS UNII (updated 2026-02-26): https://precision.fda.gov/uniisearch/
- WHO JECFA Database (updated 2026-10-04): https://apps.who.int/food-additives-contaminants-jecfa-database/Home/Chemical/3026
- openFDA Substance (updated 2026-05-24): https://api.fda.gov/other/substance.json?search=unii:N9PR3490H9
- PubChem Live Enrichment (updated 2026-05-17): https://pubchem.ncbi.nlm.nih.gov/compound/14985

_Assessed by Greenveil._