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N-substituted derivatives of p- Phenylenediamine and their salts; N- substituted derivatives of o-Phenylenediamine (1 ), with exception of those derivatives listed elsewhere in this Annex and under reference numbers 1309, 1311, and 1312 in Annex II is restricted in cosmetic products under Annex III of the EU Cosmetics Regulation (EC) 1223/2009.
p-Phenylenediamine sulfate
High concern
p-Phenylenediamine sulfate
Canonical ingredient
EPA CPDat observed this chemical in 12 composition records across product categories including Personal care.
p-Phenylenediamine and its salts is restricted in cosmetic products under Annex III of the EU Cosmetics Regulation (EC) 1223/2009.
p-Phenylenediamine sulfate
Not assessed
Sources 5Synced Sep 2013
EPA CPDat observed this chemical in 12 composition records across product categories including Personal care.
2-Methoxymethyl-p-phenylenediamine sulfate
High concern
Sources 6Synced May 2026
1,4-Benzenediamine, 2-(methoxymethyl) 1,4-Benzenediamine, 2-(methoxymethyl)-, sulfate is restricted in cosmetic products under Annex III of the EU Cosmetics Regulation (EC) 1223/2009.
N,N'-Diphenyl-p-phenylenediamine
Not assessed
Sources 5Synced Mar 2010
EPA CPDat observed this chemical in 6 composition records across product categories including Laboratory supplies, Personal care, Industrial products.
Hydroxyethyl-p-phenylenediamine sulphate
High concern
Sources 6Synced May 2026
3-(2-Hydroxyethyl)-p- phenylenediammonium sulphate is restricted in cosmetic products under Annex III of the EU Cosmetics Regulation (EC) 1223/2009.
1,2-Phenylenediamine
Critical concern
Sources 6Synced Mar 2019
o-Phenylenediamine and its salts is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.
Hydroxyethyl-p-phenylenediamine sulphate
Not assessed
Sources 5Synced May 2026
EPA CPDat observed this chemical in 2 composition records across product categories including Personal care.
N-Methyl-3-nitro-p-phenylenediamine
Critical concern
Sources 6Synced May 2026
N-Methyl-3-nitro-p-phenylenediamine and its salts, when used as a substance in hair dye products is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.