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Hexadecyl trimethyl ammonium chloride

CAS 112-02-7 · 70/100 · High conf.

Also registered as 7 other CAS numbers

53023-95-3 · 79728-63-5 · 129290-73-9 · 139272-33-6 · 146909-27-5 · 217468-43-4 · 2124222-94-0

Hexadecyl trimethyl ammonium chloride chemical structure

Concern score

70/100High concern based on regulatory listings.
High confidence

Hexadecyl trimethyl ammonium chloride in plain language

What it is

On cosmetic ingredient lists it appears as “Cetrimonium chloride (1)”.

Also known as Cetrimonium chloride (1) · Strartrimonium chloride (1) · Cetrimonium chloride · Trimethylhexadecylammonium chloride · Hexadecyltrimethylammonium chloride · N,N,N-Trimethylhexadecan-1-aminium chloride

Show all 40 names

hexadecyl(trimethyl)azanium chloride · 1-Hexadecaminium, N,N,N-trimethyl-, chloride · 1-Hexadecanaminium, N,N,N-trimethyl-, chloride · 1-Hexadecanaminium, N,N,N-trimethyl-, chloride (1:1) · Arquad pc 16-29W · Adogen 444 · Adogen 444-29 · Aliquat 6 · Ammonium, hexadecyltrimethyl-, chloride · Ammonyx Cetac · Ammonyx Cetac 30 · Arquad 16 · Arquad 16-29 · Arquad 16-50 · Cetac · Cetyltrimethyl ammonium chloride · Cetyl Trimethyl Ammonium Chloride · Dehyquart A · Genamin ctac · Htac · Intexsan CTC 29 · Intexsan CTC 50 · Jeequat CT-29 · Morpan CHA · N-hexadecyltrimethylammonium chloride · Nikkol CA-2350 · Palmityltrimethylammonium chloride · Quartamin 60W · Surfroyal CTAC · Trimethylcetylammonium chloride · Varisoft 300 · cetrimonium chloride/hexadecyl-trimethylammoniumchloride · cetyltrimethylammonium chloride · hexadecyltrimethyl ammonium chloride

What it does

Used in consumer products as a preservative, an emulsifier and a surfactant.

  • Preservative
  • Emulsifier
  • Surfactant
  • Thickener
  • Conditioner
  • Antistatic
Is it a concern?
High concern: no hazard classifications on record. It is restricted in EU cosmetics.

Why it's flagged

C16-alkyltrimethylammonium chloride C18-alkyltrimethyammonium chloride is restricted in cosmetic products under Annex III of the EU Cosmetics Regulation (EC) 1223/2009.

RestrictedEU EC — restricted

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

Restrictions first, then routine listings from published regulatory sources.

  • EU Annex III — restricted
  • EU restricted in cosmetics

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • Cleaning
  • Industrial
  • EUEC

    Annex III of EU Cosmetics Regulation (EC) 1223/2009: substances which cosmetic products must not contain except subject to the restrictions laid down. Product types: (a) Rinse-off hair products (b) Leave-on hair products (c) Leave-on face products Maximum concentration: (a) 2,5% for the individual concentrarions or the sum of the individual concentrations of cetrimonium chloride and streartrimonium chloride (b) 1,0% for the individual concentrarions or the sum of the individual concentrations of cetrimonium chloride and streartrimonium chloride (c) 0,5% for the individual concentrarions or the sum of the individual concentrations of cetrimonium chloride and… Other conditions: For purposes other than inhibiting the development of microorganisms in the product. The purpose has to be apparent from the presentation of the product.

    restricted
    View source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 2633 composition records across product categories including Personal care, Cleaning products and household care, Home maintenance. EPA CPDat classifies this chemical for functional uses including Surfactant (surface active agent), Softener and conditioner, Anti-caking agent.
    • EPA CPDat observed this chemical in 2633 composition records across product categories including Personal care, Cleaning products and household care, Home maintenance. EPA CPDat classifies this chemical for functional uses including Surfactant (surface active agent), Softener and conditioner, Anti-caking agent.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Hexadecyl trimethyl ammonium chloride. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Hexadecyl trimethyl ammonium chloride yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

6 data sources

Where this comes from

  • EU CosIng Cosmetics Regulation Annexes

    regulatory · updated 2015-06-22

    Open →
  • EPA Chemical and Products Database

    exposure · updated september 5, 2012

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often EPA CPDat has listed Hexadecyl trimethyl ammonium chloride in a product composition. These are source records, not Greenveil catalog products.

Source records

2,633

Named organisations

6

Personal careCleaning products and household careHome maintenanceCleaning and safetyRaw materials

Typical roles

PreservativeEmulsifierSurfactantThickenerConditionerAntistatic
See products using Hexadecyl trimethyl ammonium chloride →

Catalog

Found in these products

Their ingredient lists include Hexadecyl trimethyl ammonium chloride; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

Co-occurrence

Often appears with

Ingredients that frequently appear alongside Hexadecyl trimethyl ammonium chloride in the catalog.