Food use
Food-use source coverage is present in the current record.
The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.
Mixture of 5-Chloro-2-methyl-isothiazol-3(2H)-one and 2-Methylisothiazol-3(2H)-one with magnesium chloride and magnesium nitrate is listed in Annex V of the EU Cosmetics Regulation (EC) 1223/2009 (preservatives allowed in cosmetic products).
Concern score
The concern value reflects this ingredient's chemical identity — its hazard profile from the published classifications and regulatory status below — not the safety of a product it appears in. A score near 40 is the baseline for ingredients with no specific signal (water scores 40 by design), so a mid-range value is not a safety verdict.
Concern score 25/100 (minor) · high confidence.
Prevalence of METHYLISOTHIAZOLINONE in our catalog (epa_cpdat).
Products
9,337
Brands
6
Typical roles
Catalog
Context-specific fit derived from published classifications and the current ingredient evidence profile.
Food use
Food-use source coverage is present in the current record.
The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.
Fragrance avoidance
Not a strong fit for fragrance avoidance because it carries Fragrance.
Primary documents currently linked to this ingredient record.
Structured claim signals pulled from linked ingredient research.
Published jurisdiction-level classifications and regulatory designations for this ingredient.
EU
EC
Annex V of EU Cosmetics Regulation (EC) 1223/2009: preservatives allowed in cosmetic products. Product types: Rinse-off Maximum concentration: 0.0015% (of a mixture in the ratio 3:1 of 5-Chloro-2-methyl-isothiazol-3(2H)-one and 2-Methylisothiazol-3(2H)-one
EU
EC
Annex V of EU Cosmetics Regulation (EC) 1223/2009: preservatives allowed in cosmetic products. Maximum concentration: 0,0015 % Rinse-off products
US
EPA
Champoings
Pantene
The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.
The published evidence profile currently shaping this ingredient record.
EPA CPDat observed this chemical in 9337 composition records across product categories including Construction and building materials, Laboratory supplies, Cleaning and safety. EPA CPDat classifies this chemical for functional uses including Preservative, Antioxidant, Processing aids not otherwise specified.
US
FDA
FDA NDC lists this ingredient in 1 drug products and 1 package presentations.
US
FDA
openFDA substance registry classifies this ingredient as chemical.