Food use
Food-use source coverage is present in the current record.
The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.
- beauty
- cleaning
- food
- industrial
Methylisothiazolinone
CAS 26172-55-4 · 25/100 · High conf.
Preservative · Antioxidant · Biocide
Concern score
25/100Minor concern based on regulatory listings.
Well researched
Why it's flagged
Mixture of 5-Chloro-2-methyl-isothiazol-3(2H)-one and 2-Methylisothiazol-3(2H)-one with magnesium chloride and magnesium nitrate is listed in Annex V of the EU Cosmetics Regulation (EC) 1223/2009 (preservatives allowed in cosmetic products).
The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.
Regulation
No restrictions found. Methylisothiazolinone appears in these published regulatory listings.
- commercial_presence
- consumer_product_presence
- cpdat_category:beauty|cleaning|pharma|food|industrial
- definition_level:complete
- definition_type:primary
- eu_annex:V
- eu_cosmetic_allowed_preservative
- ingredient_type:ingredient substance
EUECallowed_listed2 entries
- Annex V of EU Cosmetics Regulation (EC) 1223/2009: preservatives allowed in cosmetic products. Product types: Rinse-off Maximum concentration: 0.0015% (of a mixture in the ratio 3:1 of 5-Chloro-2-methyl-isothiazol-3(2H)-one and 2-Methylisothiazol-3(2H)-oneSource →
- Annex V of EU Cosmetics Regulation (EC) 1223/2009: preservatives allowed in cosmetic products. Maximum concentration: 0,0015 % Rinse-off productsSource →
USEPAcommercial use observedEPA CPDat observed this chemical in 9337 composition records across product categories including Construction and building materials, Laboratory supplies, Cleaning and safety. EPA CPDat classifies this chemical for functional uses including Preservative, Antioxidant, Processing aids not otherwise specified.
- EPA CPDat observed this chemical in 9337 composition records across product categories including Construction and building materials, Laboratory supplies, Cleaning and safety. EPA CPDat classifies this chemical for functional uses including Preservative, Antioxidant, Processing aids not otherwise specified.Source →
USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 1 drug products and 1 package presentations.
- FDA NDC lists this ingredient in 1 drug products and 1 package presentations.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
- openFDA substance registry classifies this ingredient as chemical.Source →
Evidence
No graded sources yet for Methylisothiazolinone. We publish evidence only once a source is linked and reviewed — this ingredient is in the catalog, but has not been assessed.
Suitability
Context-specific fit derived from published classifications and the current ingredient evidence profile.
Good fit
Fragrance avoidance
Not a strong fit for fragrance avoidance because it carries Fragrance.
The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.
Where it appears
Prevalence of Methylisothiazolinone in our catalog (epa_cpdat).
Products
9,337
Brands
6
Construction and building materialsLaboratory suppliesCleaning and safetyRaw materialsHome maintenanceIndustrial products
Typical roles
PreservativeAntioxidantBiocideFragrance
Found in these products
- True Dent DentrifriceNon Food ProductsHigh
- ChampoingsPantene · Non Food ProductsHigh
- Coconut MilkHerbal Essences · Health BeautyHigh
- Golden Moringa Oil ShampooHerbal Essences · Health BeautyHigh
- JessysMinor
- Champú PANTENEttyw · Non Food ProductsHigh
- au lait 700mlpanteneHigh
- الطاووسSavon liquide · Non Open Products FactsHigh
- malizia arganHigh
- Persil lessive liquide bouquet de ProvenceHenkel, Persil · LessiveCritical
- Piel sana gel de duchaInstituto EspañolHigh
- Dettol Liquid HandwashDettol · Liquid HandwashCritical
- Leche de coco champúHerbal Essences · Non Open Products FactsHigh
- Gel de baño hidratanteNatural HoneyCritical
- Gel de baño hidratante de avenaInstituto EspañolCritical
- jabón en cremaamalfi · SHigh
- Gel Régulateur Active de Toilette Intime Soin et Prévention au CranberryIntima · HygieneHigh
- Dettol Liquid HandwashDettol · HandwashCritical
- 1751301004Critical
- Miracle Moist ShampooAussie · HairHigh
- Shampoo Miracle Moist 500 mlProcter & Gamble Norge AS · Non Food ProductsHigh
- HIMALAYA NEEM.FACE WASH 50MLHIMALAYA · Non Food ProductsHigh
- AROMA SENSE COCONUTFLORESE · HygieneHigh
- NIVEA Men Active Energy Hydraterende DagcrèmeNivea Men · BeautyCritical
Often appears with
Ingredients that frequently appear alongside Methylisothiazolinone in the catalog.
- Methylchloroisothiazolinone
- 5-Chloro-2-methyl-3(2H)-isothiazolone
- Fragrance
- 2-Methyl-3(2H)-isothiazolone
- Magnesium dinitrate hexahydrate
- Magnesium nitrate
- Methylisothiazolinone
- Beef peptone (enzymatic; 400 mw)
- Sodium O-XYLENE-4-SULFONATE
- Sodium xylenesulfonate
- Lauramidopropyl betaine
- Amides, coco, N-[3-(dimethylamino)propyl], alkylation products with chloroacetic acid, sodium salts