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5-Chloro-2-methyl-3(2H)-isothiazolone

CAS 26172-55-4

Also registered as 2 other CAS numbers

137086-87-4 · 137662-59-0

5-Chloro-2-methyl-3(2H)-isothiazolone chemical structure

Concern score

Not assessed — no hazard data yet.

5-Chloro-2-methyl-3(2H)-isothiazolone in plain language

What it is

Also known as Methylchloroisothiazolinone · 5-Chloro-2-methyl-4-isothiazolin-3-one · 5-CHLOR-2-METHYL-4-ISOTHIAZOLIN-3-ONE · 5-Chloro-2-methyl-1,2-thiazol-3(2H)-one · 5-chloro-2-methyl-1,2-thiazol-3-one · 2-METHYL-5-CHLORO isothiazolinone

Show all 29 names

2-Methyl-5-chloro-3-isothiazolone · 2-Methyl-5-chloroisothiazolin-3-one · 3(2H)-Isothiazolone, 5-chloro-2-methyl- · 5-CHLORO-2-METHYL-3(2H)-ISOTHIAZOLINONE · 5-CHLORO-2-METHYL-3-ISOTHIAZOLONE · 5-CHLORO-2-METHYL-ISOTHIAZOL-3-ONE · 5-CHLORO-2-METHYLISOTHIAZOLIN-3-ONE · 5-CHLORO-N-METHYLISOTHIAZOLIN-3-ONE · 5-CHLORO-N-METHYLISOTHIAZOLONE · 5-Chlor-2-methyl-2H-isothiazol-3-on · 5-Chloro-2-methyl-2H-isothiazol-3-one · 5-chloro-2-methyl-2H-isothiazole-3-one · 5-chloro-2-methyl-4-isothioazolin-3-one · 5-chloro-2-methyl-4-isothioazolin-3-one%: 0.0001-0.001 · 5-chloro-2-methylisothiazol-3(2h)-one · A 33 · Cmit · Chloromethylisothiazolinone · Hs 818 · Kathon CG 5243 · N-METHYL-5-CHLOROISOTHIAZOLIN-3-ONE · N-METHYL-5-CHLOROISOTHIAZOLONE · Neolone 950

What it does

Used in consumer products as an antioxidant, a preservative and a fragrance ingredient.

  • Antioxidant
  • Preservative
  • Fragrance
  • Antimicrobial
Is it a concern?
We haven't assessed a concern score for this ingredient yet.

Regulation

No restrictions found. 5-Chloro-2-methyl-3(2H)-isothiazolone appears in these published regulatory listings.

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • Cleaning
  • Industrial
  • USEPAcommercial use observedEPA CPDat observed this chemical in 6578 composition records across product categories including Laboratory supplies, Cleaning and safety, Home maintenance. EPA CPDat classifies this chemical for functional uses including Preservative, Antioxidant, Biocide.
    • EPA CPDat observed this chemical in 6578 composition records across product categories including Laboratory supplies, Cleaning and safety, Home maintenance. EPA CPDat classifies this chemical for functional uses including Preservative, Antioxidant, Biocide.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for 5-Chloro-2-methyl-3(2H)-isothiazolone. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for 5-Chloro-2-methyl-3(2H)-isothiazolone yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

5 data sources

Where this comes from

  • EPA Chemical and Products Database

    exposure · updated september 6, 2012

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.

Fragrance avoidance

Not a strong fit for fragrance avoidance because it carries Fragrance.

Avoid

The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.

Where it has been recorded

How often EPA CPDat has listed 5-Chloro-2-methyl-3(2H)-isothiazolone in a product composition. These are source records, not Greenveil catalog products.

Source records

6,578

Named organisations

6

Laboratory suppliesCleaning and safetyHome maintenanceConstructionRaw materialsSpecialty occupational products

Typical roles

AntioxidantPreservativeFragranceAntimicrobial
See products using 5-Chloro-2-methyl-3(2H)-isothiazolone →

Catalog

Found in these products

Their ingredient lists include 5-Chloro-2-methyl-3(2H)-isothiazolone; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

Co-occurrence

Often appears with

Ingredients that frequently appear alongside 5-Chloro-2-methyl-3(2H)-isothiazolone in the catalog.