Food use
Food-use source coverage is present in the current record.
The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.
Disodium 5-amino-4-hydroxy-3-(phenylazo)naphathlene-2,7-disulphonate (see note 17); (CI 17200) is restricted in cosmetic products under Annex III of the EU Cosmetics Regulation (EC) 1223/2009.
Concern score
The concern value reflects this ingredient's chemical identity — its hazard profile from the published classifications and regulatory status below — not the safety of a product it appears in. A score near 40 is the baseline for ingredients with no specific signal (water scores 40 by design), so a mid-range value is not a safety verdict.
Concern score 70/100 (high) · high confidence.
Regional restrictions
Prevalence of D&C RED NO. 33 in our catalog (epa_cpdat).
Products
1,329
Brands
6
Typical roles
Catalog
Context-specific fit derived from published classifications and the current ingredient evidence profile.
Food use
Food-use source coverage is present in the current record.
The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.
Fragrance avoidance
Not a strong fit for fragrance avoidance because it carries Fragrance.
Canonical allergen markers detected on this ingredient. Each row is derived from the ingredient’s name or synonyms matching a known allergen class — useful when scanning a label for a specific allergy context.
Source: chemindex_name_match
Primary documents currently linked to this ingredient record.
Structured claim signals pulled from linked ingredient research.
Published jurisdiction-level classifications and regulatory designations for this ingredient.
EU
EC
Annex III of EU Cosmetics Regulation (EC) 1223/2009: substances which cosmetic products must not contain except subject to the restrictions laid down. Product types: Hair dye substance in non-oxidative hair dye products Maximum concentration: 0.5 %
EU
EC
Annex IV of EU Cosmetics Regulation (EC) 1223/2009: colorants allowed in cosmetic products.
US
EPA
head and shoulders classic
Head & Shoulders
The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.
The published evidence profile currently shaping this ingredient record.
EPA CPDat observed this chemical in 1329 composition records across product categories including Personal care, Cleaning products and household care, Food and drug. EPA CPDat classifies this chemical for functional uses including Dye, Fragrance.
US
FDA
Route: ORAL; Dosage form: CAPSULE; Maximum daily exposure: 1 mg
US
FDA
Route: ORAL; Dosage form: CAPSULE, EXTENDED RELEASE; Potency: NA
US
FDA
Route: ORAL; Dosage form: CAPSULE, LIQUID FILLED; Potency: 0.01 mg
US
FDA
Route: ORAL; Dosage form: CONCENTRATE; Potency: 0.02 mg/1ml
US
FDA
Route: ORAL; Dosage form: ELIXIR; Potency: 27.5 mg/5ml
US
FDA
Route: ORAL; Dosage form: SOLUTION; Maximum daily exposure: 2 mg
US
FDA
Route: ORAL; Dosage form: SUSPENSION; Potency: 0.13 mg/5ml
US
FDA
Route: ORAL; Dosage form: SUSPENSION, EXTENDED RELEASE; Potency: NA
US
FDA
Route: ORAL; Dosage form: SYRUP; Maximum daily exposure: 1 mg
US
FDA
Route: ORAL; Dosage form: TABLET, FILM COATED; Potency: NA
US
FDA
openFDA substance registry classifies this ingredient as chemical.