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D&C red no. 33

CAS 64553-75-9 · 70/100 · High conf.

Also registered as 1 other CAS number

3567-66-6

Concern score

70/100High concern based on regulatory listings.
High confidence

D&C red no. 33 in plain language

What it is

On cosmetic ingredient lists it appears as “Acid red 33”.

Also known as Acid red 33 · CI 17200 · D & c red #33 · F d & c red #33 · FD&C red no. 33 (delisted) · Red 10B

Show all 20 names

AKA227 · Red 33 · Azofuchsin · C.I. Acid Red 33 · D.c. red no. 33 · Dc red no. 33 · Food red 12 · Acetyl Red B · Acid Fuchsin Fast B · Acid Fuchsine 38013 · CI Acid Red 33 · acid red #33 and/or · ci 17200 / acid red 33 · d&c red 33

What it does

Used in cosmetics as a colourant and a hair dye. Acid Red 33 is classed chemically as a monoazo colour.

  • Colorant
  • Hair dyeing
  • Colour
  • Colourant
  • Fragrance
Is it a concern?
High concern: no hazard classifications on record. It is restricted in EU cosmetics.

Why it's flagged

Disodium 5-amino-4-hydroxy-3-(phenylazo)naphathlene-2,7-disulphonate (see note 17); (CI 17200) is restricted in cosmetic products under Annex III of the EU Cosmetics Regulation (EC) 1223/2009.

RestrictedEU EC — restricted

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

Restrictions first, then routine listings from published regulatory sources.

  • EU Annex III — restricted
  • EU Annex IV — permitted colorant
  • EU permitted colorant
  • EU restricted in cosmetics
  • Inactive ingredient in US drugs

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • Cleaning
  • Pharma
  • Food
  • Industrial

  • EUEC

    Annex III of EU Cosmetics Regulation (EC) 1223/2009: substances which cosmetic products must not contain except subject to the restrictions laid down. Product types: Hair dye substance in non-oxidative hair dye products Maximum concentration: 0.5 %

    restricted
    View source →
  • USFDAinactive ingredient database14 entries — 3 administration routes
    • Route: ORAL; Dosage form: CAPSULE, EXTENDED RELEASE; Potency: NASource →
    • Route: ORAL; Dosage form: CAPSULE, LIQUID FILLED; Potency: 0.01 mgSource →
    • Route: ORAL; Dosage form: CONCENTRATE; Potency: 0.02 mg/1mlSource →
    • Route: ORAL; Dosage form: ELIXIR; Potency: 27.5 mg/5mlSource →
    • Route: ORAL; Dosage form: SOLUTION; Maximum daily exposure: 2 mgSource →
    • Route: ORAL; Dosage form: SUSPENSION; Potency: 0.13 mg/5mlSource →
    • Route: ORAL; Dosage form: SUSPENSION, EXTENDED RELEASE; Potency: NASource →
    • Route: ORAL; Dosage form: SYRUP; Maximum daily exposure: 1 mgSource →
    • Route: ORAL; Dosage form: TABLET; Potency: 0.24 mgSource →
    • Route: ORAL; Dosage form: TABLET, COATED; Potency: NASource →
    • Route: ORAL; Dosage form: TABLET, FILM COATED; Potency: NASource →
    • Route: TOPICAL; Dosage form: SHAMPOO; Potency: NASource →
    • Route: ORAL; Dosage form: CAPSULE; Maximum daily exposure: 1 mgSource →
    • Route: DENTAL; Dosage form: SOLUTION; Potency: NASource →
  • EUCosIngActive4 entries
    • Acid Red 33 is classed chemically as a monoazo colour. It conforms to the formula: Restriction: III/254 (Acid Red 33) IV/37 (CI 17200)Source →
    • CI 17200 is classed chemically as a monoazo colour. It conforms to the formula: Restriction: IV/37 (CI 17200) III/254 (Acid Red 33)Source →
    • Cosmetics Regulation annex III / ref 254.Source →
    • Cosmetics Regulation annex IV / ref 37.Source →
  • GLOBALJECFAEvaluated2 entries
  • EUECallowed_listedAnnex IV of EU Cosmetics Regulation (EC) 1223/2009: colorants allowed in cosmetic products.
    • Annex IV of EU Cosmetics Regulation (EC) 1223/2009: colorants allowed in cosmetic products.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 1329 composition records across product categories including Personal care, Cleaning products and household care, Food and drug. EPA CPDat classifies this chemical for functional uses including Dye, Fragrance.
    • EPA CPDat observed this chemical in 1329 composition records across product categories including Personal care, Cleaning products and household care, Food and drug. EPA CPDat classifies this chemical for functional uses including Dye, Fragrance.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

Independent scientific assessments cited by the records we hold, with the year and link where the record gives one.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

  • JECFA

    Joint FAO/WHO Expert Committee on Food Additives

    • JECFA evaluation record. Functional class: colour.

      Year not recorded · GLOBAL JECFA listing · Read the source →

    • JECFA evaluation record.

      Year not recorded · GLOBAL JECFA listing · Read the source →

Evidence & sources

No graded research studies for D&C red no. 33 yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

8 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →

  • EU CosIng Cosmetics Regulation Annexes

    regulatory · updated 2020-08-14

    Open →

  • EPA Chemical and Products Database

    exposure · updated september 8, 2015

    Open →

  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →

  • FDA Inactive Ingredient Database

    regulatory · updated 2026-01-09

    Open →

  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →

  • WHO JECFA Database

    regulatory · updated 2026-10-04

    Open →

  • openFDA Substance

    registry · updated 2026-05-24

    Open →

Allergen profile

Canonical allergen markers detected on this ingredient. Each row is derived from the ingredient’s name or synonyms matching a known allergen class — useful when scanning a label for a specific allergy context.

  • GlutenContains · Oral (ingested)

    Source: chemindex_name_match

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

Not a strong fit for fragrance avoidance because it carries Fragrance.

Avoid

The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.

Where it has been recorded

How often EPA CPDat has listed D&C red no. 33 in a product composition. These are source records, not Greenveil catalog products.

Source records

1,329

Named organisations

6

Personal careCleaning products and household careFood and drugConstructionCleaning and safety

Typical roles

ColorantHair dyeingColourColourantFragrance
See products using D&C red no. 33 →

Catalog

Found in these products

Their ingredient lists include D&C red no. 33; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 835 →Find products without it →

Co-occurrence

Often appears with

Ingredients that frequently appear alongside D&C red no. 33 in the catalog.