Dehydroacetic acid

Dehydroacetic acid in plain language

What it is

On cosmetic ingredient lists it appears as “Sodium dehydroacetate”.

Also known as Sodium dehydroacetate · 3-Acetyl-6-methylpyran-2,4(3H)-dione and its salts · 3-Acetyl-6-methyl-2H-pyran-2,4(3H)-dione · Acetic acid, dehydro- · Dehydracetic acid · Dehydroacetate

Show all 19 names

Dehydroacetic acid / SODIUM DEHYDROACETATE · 2H-PYRAN-2-ONE, 3-ACETYL-4-HYDROXY-6-METHYL- · 3-ACETYL-4-HYDROXY-6-METHYL-2-PYRONE · 3-ACETYL-4-HYDROXY-6-METHYL-2H-PYRAN-2-ONE · 3-Acetyl-6-methyl-1-oxacyclohex-5-ene-2,4-dione · 3-Acetyl-6-methyl-2,4-pyrandione · 3-Acetyl-6-methyl-2H-pyran-2,4(3H)-dion · 3-acetil-6-metil-2H-pirano-2,4(3H)-diona · 4H-PYRAN-4-ONE, 3-ACETYL-2-HYDROXY-6-METHYL- · Biocide 470F · Dhs · Geogard 111A · dehydro acetic acid

What it does

Used in cosmetics as a preservative. Dehydroacetic Acid is the cyclic ketone.

• Preservative
• Antioxidant
• Fragrance
• Antimicrobial

Is it a concern?

Minor concern: no hazard classifications on record. It is listed for cosmetic use in the EU.

What the listings say

Permitted, with conditions — Dehydroacetic acid appears on published "allowed" regulatory lists rather than on a restriction list.

3-Acetyl-6-methylpyran-2,4(3H)-dione and its salts is listed in Annex V of the EU Cosmetics Regulation (EC) 1223/2009 (preservatives allowed in cosmetic products).

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

• EU Annex V — permitted preservative
• EU permitted preservative
• Inactive ingredient in US drugs
• In marketed US drugs

• EU·CosIng·Active3 entries

  • Cosmetics Regulation annex V / ref 13.Source →
  • Dehydroacetic Acid is the cyclic ketone that conforms to the formula: Restriction: V/13Source →
  • Sodium Dehydroacetate is the heterocyclic compound that conforms generally to the formula: Restriction: V/13Source →
• US·FDA·inactive ingredient database2 entries

  • Route: TOPICAL; Dosage form: LOTION; Maximum daily exposure: 1 mgSource →
  • Route: TOPICAL; Dosage form: SHAMPOO; Potency: NASource →
• EU·EC·allowed_listedAnnex V of EU Cosmetics Regulation (EC) 1223/2009: preservatives allowed in cosmetic products. Maximum concentration: 0.6% (as acid) Other conditions: Not to be used in aerosol dispensers (sprays)

  • Annex V of EU Cosmetics Regulation (EC) 1223/2009: preservatives allowed in cosmetic products. Maximum concentration: 0.6% (as acid) Other conditions: Not to be used in aerosol dispensers (sprays)Source →
• US·EPA·commercial use observedEPA CPDat observed this chemical in 1328 composition records across product categories including Laboratory supplies, Personal care. EPA CPDat classifies this chemical for functional uses including Biocide, Preservative, Fragrance.

  • EPA CPDat observed this chemical in 1328 composition records across product categories including Laboratory supplies, Personal care. EPA CPDat classifies this chemical for functional uses including Biocide, Preservative, Fragrance.Source →
• US·FDA·marketed drug occurrenceFDA NDC lists this ingredient in 5 drug products and 5 package presentations.

  • FDA NDC lists this ingredient in 5 drug products and 5 package presentations.Source →
• US·FDA·listed in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.

  • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Dehydroacetic acid. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

• SCCS

  EU Scientific Committee on Consumer Safety

  No SCCS opinion on file.

• CIR

  Cosmetic Ingredient Review (US expert panel)

  No CIR safety assessment on file.

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• Co occurs
• 3-Acetyl-2-hydroxy-6-methyl-4H-pyran-4-oneCo occurs
• 3-Acetyl-4-hydroxy-6-methyl-2H-pyran-2-oneCo occurs
• LysineCo occurs
• GlycerinCo occurs