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m-Aminophenol and its salts

CAS 51-81-0 · 70/100 · High conf.

Also registered as 3 other CAS numbers

591-27-5 · 38171-54-9 · 68239-81-6

m-Aminophenol and its salts chemical structure

Concern score

70/100High concern based on regulatory listings.
High confidence

m-Aminophenol and its salts in plain language

What it is

On cosmetic ingredient lists it appears as “M-aminophenol”.

Also known as M-aminophenol · M-aminophenol hcl · M-aminophenol sulfate · 3-AMINOPHENOL hydrochloride · 3-Aminophenol · 3-Hydroxyanilinium chloride

Show all 16 names

Phenol, 3-​amino-​, hydrochloride (1:1) · (3-hydroxyphenyl)azanium chloride · 3-Aminophenol--hydrogen chloride (1/1) · M-aminophenol; m-aminophenol hcl; m-aminophenol sulfate · (3-hydroxyphenyl)azanium;chloride · 3-Aminophenol (CI 76545) · M-aminophenol hydrochloride · Phenol, 3-AMINO-, hydrochloride · Phenol, 3-amino-, hydrochloride (1:1) · UNII-NQM2XX7XPO

What it does

Used in cosmetics as a hair dye.

  • Hair dyeing
  • Colourant
Is it a concern?
High concern: no hazard classifications on record. It is restricted in EU cosmetics.

Why it's flagged

m-Aminophenol and its salts is restricted in cosmetic products under Annex III of the EU Cosmetics Regulation (EC) 1223/2009.

RestrictedEU EC — restricted

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

Restrictions first, then routine listings from published regulatory sources.

  • EU Annex III — restricted
  • EU restricted in cosmetics

Recorded in these product areas

  • Found in consumer products
  • Industrial

  • EUEC

    Annex III of EU Cosmetics Regulation (EC) 1223/2009: substances which cosmetic products must not contain except subject to the restrictions laid down. Product types: (a) Hair dye substance in oxidative hair dye products (b) Products intended for colouring eyelashes Other conditions: For (a) and (b): After mixing under oxidative conditions the maximum concentration applied to hair or eyelashes must not exceed 1,2 % (b) For professional use only Conditions of use and warnings: (a) To be printed on the label: The mixing ratio. “ Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy.Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever…

    restricted
    View source →
  • EUCosIngActive2 entries
  • EUEFSAConclusion on Pesticides Peer ReviewPeer review of the pesticide risk assessment of the active substance desmedipham (EFSA)
    • Peer review of the pesticide risk assessment of the active substance desmedipham (EFSA)Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Dye.
    • EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Dye.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

Independent scientific assessments cited by the records we hold, with the year and link where the record gives one.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

  • EFSA

    European Food Safety Authority

    • Peer review of the pesticide risk assessment of the active substance desmedipham (EFSA)

      2018 · EU EFSA listing · Read the source →

Evidence & sources

No graded research studies for m-Aminophenol and its salts yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

8 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →

  • EU CosIng Cosmetics Regulation Annexes

    regulatory · updated 2014-02-14

    Open →

  • EFSA OpenFoodTox

    regulatory · updated 2026-10-02

    Open →

  • EPA Chemical and Products Database

    exposure · updated 2019-12-20

    Open →

  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →

  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →

  • openFDA Substance

    registry · updated 2026-05-24

    Open →

  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Catalog

Found in these products

Their ingredient lists include m-Aminophenol and its salts; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 142 →Find products without it →

Co-occurrence

Often appears with

Ingredients that frequently appear alongside m-Aminophenol and its salts in the catalog.