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Cellulase

CAS 62213-14-3 · 40/100 · High conf.

Also registered as 12 other CAS numbers

143296-48-4 · 145172-25-4 · 149718-64-9 · 152443-09-9 · 160995-61-9 · 179530-34-8 · 214975-89-0 · 881098-86-8 · 2242562-77-0 · 9012-54-8 · 9025-57-4 · 9037-40-5

Concern score

40/100Moderate concern based on regulatory listings.
High confidence

Cellulase in plain language

What it is

Also known as Cellulase (trichoderma longibrachiatum) · CELLULASE from TRICHODERMA LONGIBRACHIATUM · Endoglucanase EG-1 (trichoderma longibrachiatum) · 1,4-β-D-Endoglucanase · 1,4-β-D-Glucan 4-glucanohydrolase · 1,4-β-D-Glucan endoglucanase

Show all 13 names

1,4-β-Glycanase · Acidic Cellulase AE 202 · Acidic Cellulase AE202 · Acremozyme · Alkali cellulase · Cellulase / Hemicellulase Enzyme · Cellulase enzyme

What it does

Used in cosmetics as a keratolytic, an oral-care ingredient and a thickener. Cellulase is an enzyme that hydrolyzes cellulose.

  • Keratolytic
  • Oral care
  • Viscosity controlling
  • Enzyme preparation
  • Thickener
  • Stabiliser
Is it a concern?
Moderate concern: no hazard classifications on record. It is listed for cosmetic use in the EU.

Why it's flagged

EPA CPDat observed this chemical in 79 composition records across product categories including Cleaning products and household care, Home maintenance.

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

No restrictions found. Cellulase appears in these published regulatory listings.

Recorded in these product areas

  • Found in consumer products
  • Cleaning
  • EUCosIngActiveCellulase is an enzyme that hydrolyzes cellulose
    • Cellulase is an enzyme that hydrolyzes celluloseSource →
  • GLOBALJECFANOT SPECIFIEDJECFA evaluation lists ADI NOT SPECIFIED. Functional class: enzyme preparation.
    • JECFA evaluation lists ADI NOT SPECIFIED. Functional class: enzyme preparation.Source →
  • GLOBALJECFANOT SPECIFIED (TEMPORARY)JECFA evaluation lists ADI NOT SPECIFIED (TEMPORARY). Functional class: enzyme preparation.
    • JECFA evaluation lists ADI NOT SPECIFIED (TEMPORARY). Functional class: enzyme preparation.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 79 composition records across product categories including Cleaning products and household care, Home maintenance. EPA CPDat classifies this chemical for functional uses including Cleaning agent, Chemical reaction regulator, Viscosity modifier.
    • EPA CPDat observed this chemical in 79 composition records across product categories including Cleaning products and household care, Home maintenance. EPA CPDat classifies this chemical for functional uses including Cleaning agent, Chemical reaction regulator, Viscosity modifier.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as protein.
    • openFDA substance registry classifies this ingredient as protein.Source →

Expert safety opinions

Independent scientific assessments cited by the records we hold, with the year and link where the record gives one.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

  • JECFA

    Joint FAO/WHO Expert Committee on Food Additives

    • JECFA evaluation lists ADI NOT SPECIFIED. Functional class: enzyme preparation.

      Year not recorded · GLOBAL JECFA listing · Read the source →

    • JECFA evaluation lists ADI NOT SPECIFIED (TEMPORARY). Functional class: enzyme preparation.

      Year not recorded · GLOBAL JECFA listing · Read the source →

Evidence & sources

No graded research studies for Cellulase yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

6 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →

  • EPA Chemical and Products Database

    exposure · updated January 7, 2008

    Open →

  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →

  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →

  • WHO JECFA Database

    regulatory · updated 2026-10-04

    Open →

  • openFDA Substance

    registry · updated 2026-05-24

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often EPA CPDat has listed Cellulase in a product composition. These are source records, not Greenveil catalog products.

Source records

79

Named organisations

6

Cleaning products and household careHome maintenance

Typical roles

KeratolyticOral careViscosity controllingEnzyme preparationThickenerStabiliser
See products using Cellulase →

Catalog

Found in these products

Their ingredient lists include Cellulase; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 224 →Find products without it →

Co-occurrence

Often appears with

Ingredients that frequently appear alongside Cellulase in the catalog.