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Trehalose

CAS 229966-89-6 · 40/100 · High conf.

Also registered as 2 other CAS numbers

1898191-27-9 · 99-20-7

Trehalose chemical structure

Concern score

40/100Moderate concern based on regulatory listings.
High confidence

Trehalose in plain language

What it is

Also known as D-Trehalose · alpha-TREHALOSE alpha · .alpha.,.alpha.-trehalose · Mushroom sugar · Mycose · alpha-D-Glucopyranosyl alpha-D-glucopyranoside

Show all 22 names

.alpha.-d-glucopyranosyl-.alpha.-d-glucopyranoside · Cabaletta · D-(+)-Trehalose · Ergot sugar · G92130SN · GlyTouCan:G92130SN · Natural trehalose · O-D-Glucopyranosyl-(1→1)-D-glucopyranoside · Thealoz · Treha · Trehalose 100PH · Trehaose · alpha'-Trehalose alpha · alpha-D-Trehalose · zozu abundant charming hips cream · zozu plump beautiful breast cream

What it does

Used in cosmetics as a humectant and a moisturiser.

  • Humectant
  • Moisturising
  • Texturizer, thickener, humectant, stabilizer, sweetener
  • Flavouring
  • Conditioner
Is it a concern?
Moderate concern: no hazard classifications on record. It is listed for cosmetic use in the EU.

Why it's flagged

EPA CPDat observed this chemical in 754 composition records across product categories including Personal care, Batteries.

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

No restrictions found. Trehalose appears in these published regulatory listings.

  • In marketed US drugs

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • Cleaning
  • EUCosIngActiveListed in CosIng inventory for cosmetic use.
    • Listed in CosIng inventory for cosmetic use.Source →
  • GLOBALJECFANOT SPECIFIEDJECFA evaluation lists ADI NOT SPECIFIED. Functional class: texturizer, thickener, humectant, stabilizer, sweetener.
    • JECFA evaluation lists ADI NOT SPECIFIED. Functional class: texturizer, thickener, humectant, stabilizer, sweetener.Source →
  • GLOBALJECFAEvaluatedJECFA evaluation record.
  • USEPAcommercial use observedEPA CPDat observed this chemical in 754 composition records across product categories including Personal care, Batteries. EPA CPDat classifies this chemical for functional uses including Humectant, Flavouring and nutrient, Softener and conditioner.
    • EPA CPDat observed this chemical in 754 composition records across product categories including Personal care, Batteries. EPA CPDat classifies this chemical for functional uses including Humectant, Flavouring and nutrient, Softener and conditioner.Source →
  • USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 2 active drug products and 2 total products.
    • FDA NDC lists this ingredient in 2 active drug products and 2 total products.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

Independent scientific assessments cited by the records we hold, with the year and link where the record gives one.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

  • JECFA

    Joint FAO/WHO Expert Committee on Food Additives

    • JECFA evaluation lists ADI NOT SPECIFIED. Functional class: texturizer, thickener, humectant, stabilizer, sweetener.

      Year not recorded · GLOBAL JECFA listing · Read the source →

    • JECFA evaluation record.

      Year not recorded · GLOBAL JECFA listing · Read the source →

Evidence & sources

No graded research studies for Trehalose yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

8 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EPA Chemical and Products Database

    exposure · updated September 2018

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA National Drug Code Directory

    regulatory · updated 2026-12-31

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • WHO JECFA Database

    regulatory · updated 2026-10-04

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Allergen profile

Canonical allergen markers detected on this ingredient. Each row is derived from the ingredient’s name or synonyms matching a known allergen class — useful when scanning a label for a specific allergy context.

  • DairyContains · Oral (ingested)

    Source: chemindex_name_match

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often EPA CPDat has listed Trehalose in a product composition. These are source records, not Greenveil catalog products.

Source records

754

Named organisations

6

Personal careBatteries

Typical roles

HumectantMoisturisingTexturizer, thickener, humectant, stabilizer, sweetenerFlavouringConditioner
See products using Trehalose →

Catalog

Found in these products

Their ingredient lists include Trehalose; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

Co-occurrence

Often appears with

Ingredients that frequently appear alongside Trehalose in the catalog.