beauty
cleaning
food
industrial

Saccharin sodium anhydrous

CAS 38279-26-4 · 40/100 · High conf.

Also registered as 3 other CAS numbers

1792234-08-2 · 128-44-9 · 6155-57-3

Saccharin sodium anhydrous chemical structure

Concern score

40/100Moderate concern based on regulatory listings.

High confidence

Saccharin sodium anhydrous in plain language

What it is: On cosmetic ingredient lists it appears as “Sodium saccharin”.
Also known as Sodium saccharin · Saccharin sodium · Saccharin sodium salt · Anhydrous saccharin sodium · 1,2-Benzisothiazol-3(2H)-one 1,1-dioxide sodium salt · 1,2-BENZISOTHIAZOL-3(2H)-ONE, 1,1-DIOXIDE, sodium salt
Show all 35 names
1,2-BENZISOTHIAZOLIN-3-ONE 1,1-DIOXIDE sodium salt · Anhydrous sodium saccharin · sodium 1,1-dioxo-1,2-benzothiazol-2-id-3-one · 1,1-Dioxyde de 1,2-benzisothiazol-3(2H)-one, sel de sodium · 1,1-dioxido de 1,2-bencisotiazol-3(2H)-ona, sal sodica · 1,1-dioxyde de 1,2-benzisothiazole-3(2H)-one, sel de sodium · 1,2-BENZISOTHIAZOL-IN-3-ONE, 1,1-DIOXIDE sodium salt · 1,2-Benzisothiazol-3(2H)-on-1,1-dioxid, Natriumsalz · 1,2-Benzisothiazol-3(2H)-one 1,1-dioxide, sodium salt · 1,2-Benzisothiazol-3(2H)-one, 1,1-dioxide, sodium salt (1:1) · 1,2-Benzisothiazolin-3-one, 1,1-dioxide, sodium deriv. · Crystallose · Dagutan · Kristallose · Madhurin · Saccharin soluble · Saccharine sodium salt · Saccharine soluble · Saccharinnatrium · Saccharoidum natricum · Sodium benzosulphimide · Sodium saccharide · Sodium saccharinate · Soluble gluside · Sucra · Sucromat · Willosetten · sodium saccharine · saccharinum natricum
What it does: Used in cosmetics as a flavouring, an oral-care ingredient and a fragrance ingredient.
Flavouring
Oral care
Fragrance
Sweetener
Solvent
Deodorant
Is it a concern?: Moderate concern: no hazard classifications on record. It is listed for cosmetic use in the EU.

Why it's flagged

EPA CPDat observed this chemical in 1394 composition records across product categories including Medical/dental, Food and drug, Cleaning and safety.

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

No restrictions found. Saccharin sodium anhydrous appears in these published regulatory listings.

Inactive ingredient in US drugs

Recorded in these product areas

Found in consumer products
Beauty
Cleaning
Pharma
Food
Industrial

USFDAinactive ingredient database17 entries — 7 administration routes
- Route: INTRAVENOUS; Dosage form: INJECTION; Potency: 0.09 %w/vSource →
- Route: NASAL; Dosage form: DROPS; Potency: 0.5 mg/1mlSource →
- Route: NASAL; Dosage form: SOLUTION; Potency: 0.5 mg/1mlSource →
- Route: ORAL; Dosage form: EMULSION; Potency: 0.4 mg/1mlSource →
- Route: ORAL; Dosage form: LIQUID; Potency: 1.5 mg/5mlSource →
- Route: ORAL; Dosage form: POWDER, FOR SUSPENSION; Potency: 18.75 mg/5mlSource →
- Route: ORAL; Dosage form: SOLUTION; Maximum daily exposure: 20 mgSource →
- Route: ORAL; Dosage form: SUSPENSION; Potency: 16.65 mg/5mlSource →
- Route: INTRAMUSCULAR; Dosage form: INJECTION; Potency: 0.09 %w/vSource →
- Route: ORAL; Dosage form: TABLET; Potency: 97 mgSource →
- Route: ORAL; Dosage form: TABLET, CHEWABLE; Potency: 7.5 mgSource →
- Route: ORAL; Dosage form: TABLET, FILM COATED; Potency: 0.35 mgSource →
- Route: ORAL; Dosage form: WAFER; Potency: 4.8 mgSource →
- Route: RECTAL; Dosage form: SOLUTION; Potency: 0.67 %w/vSource →
- Route: DENTAL; Dosage form: PASTE, DENTIFRICE; Potency: 0.15 %w/wSource →
- Route: BUCCAL; Dosage form: MOUTHWASH; Potency: 0.2 mg/1mlSource →
- Route: ORAL; Dosage form: SYRUP; Potency: 3.96 mg/5mlSource →
EUEFSAEFSA opinion2 entries
- Safety and efficacy of sodium saccharin when used as a feed flavour for piglets, pigs for fattening, calves for rearing and calves for fattening (EFSA FEEDAP)Source →
- Scientific Opinion on the safety evaluation of the substance, 1,2-benzisothiazol-3(2H)-one 1,1-dioxide, sodium salt , CAS No. 128-44-9, for use in food contact materials - EFSA Panel on food contact materials, enzymes, flavourings and processing aids (CEF) (EFSA CEF)Source →
EUCosIngActiveListed in CosIng inventory for cosmetic use.
- Listed in CosIng inventory for cosmetic use.Source →
GLOBALJECFA0-5 mg/kg bwJECFA evaluation lists ADI 0-5 mg/kg bw. Functional class: sweetener.
- JECFA evaluation lists ADI 0-5 mg/kg bw. Functional class: sweetener.Source →
USEPAcommercial use observedEPA CPDat observed this chemical in 1394 composition records across product categories including Medical/dental, Food and drug, Cleaning and safety. EPA CPDat classifies this chemical for functional uses including Flavouring and nutrient, Deodorizer, oral care.
- EPA CPDat observed this chemical in 1394 composition records across product categories including Medical/dental, Food and drug, Cleaning and safety. EPA CPDat classifies this chemical for functional uses including Flavouring and nutrient, Deodorizer, oral care.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
- openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

Independent scientific assessments cited by the records we hold, with the year and link where the record gives one.

SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.
EFSA
European Food Safety Authority
- Safety and efficacy of sodium saccharin when used as a feed flavour for piglets, pigs for fattening, calves for rearing and calves for fattening (EFSA FEEDAP)
  2018 · EU EFSA listing · Read the source →
- Scientific Opinion on the safety evaluation of the substance, 1,2-benzisothiazol-3(2H)-one 1,1-dioxide, sodium salt , CAS No. 128-44-9, for use in food contact materials - EFSA Panel on food contact materials, enzymes, flavourings and processing aids (CEF) (EFSA CEF)
  2012 · EU EFSA listing · Read the source →
JECFA
Joint FAO/WHO Expert Committee on Food Additives
- JECFA evaluation lists ADI 0-5 mg/kg bw. Functional class: sweetener.
  Year not recorded · GLOBAL JECFA listing · Read the source →

Evidence & sources

No graded research studies for Saccharin sodium anhydrous yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

9 data sources

Where this comes from

CosIng
regulatory · updated 2026-09-23
Open →
EFSA OpenFoodTox
regulatory · updated 2026-10-04
Open →
EPA Chemical and Products Database
exposure · updated september 6, 2017
Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
Open →
FDA Inactive Ingredient Database
regulatory · updated 2026-01-09
Open →
FDA GSRS UNII
registry · updated 2026-02-26
Open →
WHO JECFA Database
regulatory · updated 2026-10-04
Open →
openFDA Substance
registry · updated 2026-05-24
Open →
PubChem Live Enrichment
chemistry · updated 2026-05-17
Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

Not a strong fit for fragrance avoidance because it carries Fragrance.

Avoid

The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.

Where it has been recorded

How often EPA CPDat has listed Saccharin sodium anhydrous in a product composition. These are source records, not Greenveil catalog products.

Source records

1,394

Named organisations

Medical/dentalFood and drugCleaning and safetyLaboratory suppliesPersonal carePet and animal care

Typical roles

FlavouringOral careFragranceSweetenerSolventDeodorant

See products using Saccharin sodium anhydrous →

Catalog

Found in these products

Their ingredient lists include Saccharin sodium anhydrous; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 1000+ →Find products without it →

Co-occurrence

Often appears with

Ingredients that frequently appear alongside Saccharin sodium anhydrous in the catalog.