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Hexylene glycol

CAS 102601-24-1

Also registered as 2 other CAS numbers

99113-75-4 · 107-41-5

Hexylene glycol chemical structure

Concern score

Not assessed — no hazard data yet.

Hexylene glycol in plain language

What it is

Also known as 2-Methyl-2,4-pentanediol · 2-Methylpentane-2,4-diol · (+/-)-2-Methyl-2,4-pentanediol · 1,1,3-Trimethyltrimethylenediol · 1,3,3-trimethyl-1,3-propanediol · 1,3-dimethyl-3-hydroxybutanol

Show all 17 names

2,4-Dihydroxy-2-methylpentane · 2,4-Pentanediol, 2-methyl- · 2-Methyl pentane-2,4-diol · 2-Methyl-2,4-pentandiol · 4-Methyl-2,4-pentanediol · Diolane · Hexasol · Isol · Pinakon · alpha,alpha,alpha'-Trimethyltrimethylene glycol · α,α,α′-Trimethyltrimethylene glycol

What it does

Used in cosmetics as an emulsifier, a solvent and a skin-conditioning agent.

  • Emulsifying
  • Solvent
  • Skin conditioning
  • Cleansing
  • Perfuming
  • Emulsifier
Is it a concern?
We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

Regulation

No restrictions found. Hexylene glycol appears in these published regulatory listings.

  • Inactive ingredient in US drugs

Recorded in these product areas

  • Found in consumer products
  • Cleaning
  • Industrial
  • USFDAinactive ingredient database4 entries
    • Route: TOPICAL; Dosage form: CREAM; Maximum daily exposure: 385 mgSource →
    • Route: TOPICAL; Dosage form: GEL; Maximum daily exposure: 280 mgSource →
    • Route: TOPICAL; Dosage form: OINTMENT; Potency: 12 %w/wSource →
    • Route: TOPICAL; Dosage form: SOLUTION; Potency: 0.3 %w/wSource →
  • EUCosIngActiveListed in CosIng inventory for cosmetic use.
    • Listed in CosIng inventory for cosmetic use.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 3903 composition records across product categories including Industrial products, Cleaning and safety, Furniture and furnishings. EPA CPDat classifies this chemical for functional uses including Solvent, Surfactant (surface active agent), Softener and conditioner.
    • EPA CPDat observed this chemical in 3903 composition records across product categories including Industrial products, Cleaning and safety, Furniture and furnishings. EPA CPDat classifies this chemical for functional uses including Solvent, Surfactant (surface active agent), Softener and conditioner.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Hexylene glycol. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Hexylene glycol yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

7 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →

  • EPA Chemical and Products Database

    exposure · updated september 17, 2016

    Open →

  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →

  • FDA Inactive Ingredient Database

    regulatory · updated 2026-01-09

    Open →

  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →

  • openFDA Substance

    registry · updated 2026-05-24

    Open →

  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Not a strong fit for fragrance avoidance because it carries Fragrance.

Avoid

The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.

Where it has been recorded

How often EPA CPDat has listed Hexylene glycol in a product composition. These are source records, not Greenveil catalog products.

Source records

3,903

Named organisations

6

Industrial productsCleaning and safetyFurniture and furnishingsUnknown or IndeterminateCleaning products and household careLaboratory supplies

Typical roles

EmulsifyingSolventSkin conditioningCleansingPerfumingEmulsifier
See products using Hexylene glycol →

Catalog

Found in these products

Cosmetic and personal-care products that list Hexylene glycol are shown first. Their ingredient lists include Hexylene glycol; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 465 →Find products without it →

Co-occurrence

Often appears with

Ingredients that frequently appear alongside Hexylene glycol in the catalog.