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Ribose

CAS 613-83-2 · 40/100 · High conf.

Also registered as 5 other CAS numbers

10257-32-6 · 58-91-3 · 6915-40-8 · 93781-19-2 · 50-69-1

Ribose chemical structure

Concern score

40/100Moderate concern based on regulatory listings.
High confidence

Ribose in plain language

What it is

Also known as D-ribose · Ribose, d- · RIBO-2,3,4,5-TETRAHYDROXYVALERALDEHYDE, d- · (2R,3R,4R)-2,3,4,5-tetrahydroxypentanal · (3R,4R,5R)-TETRAHYDRO-2H-PYRAN-2,3,4,5-TETRAOL · (3R,4S,5R)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-2,3,4-TRIOL

Show all 8 names

D-ribosa · Riboxyl

What it does

Used in cosmetics as a humectant and a skin-conditioning agent.

  • Humectant
  • Skin conditioning
  • Flavouring
  • Conditioner
Is it a concern?
Moderate concern: no hazard classifications on record. It is listed for cosmetic use in the EU.

Why it's flagged

EPA CPDat observed this chemical in 4 composition records across product categories including Personal care.

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

No restrictions found. Ribose appears in these published regulatory listings.

  • In marketed US drugs

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • Cleaning
  • EUEFSAEFSA opinion2 entries
    • Statement on the safety of D-ribose (EFSA NDA)Source →
    • Safety of D-ribose as a novel food pursuant to Regulation (EU) 2015/2283 (EFSA NDA)Source →
  • EUCosIngActiveListed in CosIng inventory for cosmetic use.
    • Listed in CosIng inventory for cosmetic use.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 4 composition records across product categories including Personal care. EPA CPDat classifies this chemical for functional uses including Humectant, Softener and conditioner, Flavouring and nutrient.
    • EPA CPDat observed this chemical in 4 composition records across product categories including Personal care. EPA CPDat classifies this chemical for functional uses including Humectant, Softener and conditioner, Flavouring and nutrient.Source →
  • USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 1 active drug products and 1 total products.
    • FDA NDC lists this ingredient in 1 active drug products and 1 total products.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

Independent scientific assessments cited by the records we hold, with the year and link where the record gives one.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

  • EFSA

    European Food Safety Authority

    • Statement on the safety of D-ribose (EFSA NDA)

      2018 · EU EFSA listing · Read the source →

    • Safety of D-ribose as a novel food pursuant to Regulation (EU) 2015/2283 (EFSA NDA)

      2018 · EU EFSA listing · Read the source →

Evidence & sources

No graded research studies for Ribose yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

7 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →

  • EFSA OpenFoodTox

    regulatory · updated 2026-10-04

    Open →

  • EPA Chemical and Products Database

    exposure · updated July 2018

    Open →

  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →

  • FDA National Drug Code Directory

    regulatory · updated 2026-12-31

    Open →

  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →

  • openFDA Substance

    registry · updated 2026-05-24

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often EPA CPDat has listed Ribose in a product composition. These are source records, not Greenveil catalog products.

Source records

4

Named organisations

6

Personal care

Typical roles

HumectantSkin conditioningFlavouringConditioner
See products using Ribose →

Catalog

Found in these products

Their ingredient lists include Ribose; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 44 →Find products without it →