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Sodium chlorite

CAS 66554-51-6 · 40/100 · High conf.

Also registered as 3 other CAS numbers

1352826-56-2 · 2674135-33-0 · 7758-19-2

Sodium chlorite chemical structure

Concern score

40/100Moderate concern based on regulatory listings.
High confidence

Sodium chlorite in plain language

What it is

Also known as Stabilized oxychloro complex · NACLO2 · Oxychloro complex · Soc · Alcide LD · Atlas Prep Base

Show all 29 names

Auto-Chlor Base · Aztec Gold · Chlorite de sodium · Chlorite sodium · sodium salt Chlorous acid · Chlorous acid, sodium salt (1:1) · Chloroxide B · Dioxychlor · Doctor GuardStick · Duet Base · Duet Clear Base · EasyStick · Maracyn Oxy · Natriumchlorit · Neo Silox D · Opti-Guard Base · Orbit Clean Base · Purite · Textone · clorito de sodio · sodium chlorite. pel/tlv for chloride dioxide gas. · sodiumchlorite · sodium chlorite solution

What it does

Used in cosmetics as an oral-care ingredient and an oxidising agent.

  • Oral care
  • Oxidising
  • Preservative
  • Antimicrobial
Is it a concern?
Moderate concern: no hazard classifications on record. It is listed for cosmetic use in the EU.

Why it's flagged

EPA CPDat observed this chemical in 36 composition records across product categories including Laboratory supplies, Construction and building materials, Batteries.

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

No restrictions found. Sodium chlorite appears in these published regulatory listings.

  • In marketed US drugs
  • Inactive ingredient in US drugs

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • Cleaning
  • Industrial
  • USFDAinactive ingredient database2 entries
    • Route: OPHTHALMIC; Dosage form: SOLUTION/ DROPS; Potency: 0.01 %w/vSource →
    • Route: OPHTHALMIC; Dosage form: SOLUTION; Potency: 0.01 %w/vSource →
  • USFDAlisted in openFDA substance2 entries
    • openFDA substance registry classifies this ingredient as chemical.Source →
    • openFDA substance registry classifies this ingredient as concept.Source →
  • EUCosIngActiveListed in CosIng inventory for cosmetic use.
    • Listed in CosIng inventory for cosmetic use.Source →
  • EUEFSAEFSA opinionOpinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to Treatment of poultry carcasses with chlorine dioxide, acidified sodium chlorite, trisodium phosphate and peroxyacids (EFSA AFC)
    • Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to Treatment of poultry carcasses with chlorine dioxide, acidified sodium chlorite, trisodium phosphate and peroxyacids (EFSA AFC)Source →
  • GLOBALJECFAEvaluatedJECFA evaluation record. Functional class: preservative.
    • JECFA evaluation record. Functional class: preservative.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 36 composition records across product categories including Laboratory supplies, Construction and building materials, Batteries. EPA CPDat classifies this chemical for functional uses including oral care, Oxidizing agent, Oral Care Agent.
    • EPA CPDat observed this chemical in 36 composition records across product categories including Laboratory supplies, Construction and building materials, Batteries. EPA CPDat classifies this chemical for functional uses including oral care, Oxidizing agent, Oral Care Agent.Source →
  • USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 11 active drug products and 11 total products.
    • FDA NDC lists this ingredient in 11 active drug products and 11 total products.Source →

Expert safety opinions

Independent scientific assessments cited by the records we hold, with the year and link where the record gives one.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

  • EFSA

    European Food Safety Authority

    • Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to Treatment of poultry carcasses with chlorine dioxide, acidified sodium chlorite, trisodium phosphate and peroxyacids (EFSA AFC)

      2006 · EU EFSA listing · Read the source →

  • JECFA

    Joint FAO/WHO Expert Committee on Food Additives

    • JECFA evaluation record. Functional class: preservative.

      Year not recorded · GLOBAL JECFA listing · Read the source →

Evidence & sources

No graded research studies for Sodium chlorite yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

10 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EFSA OpenFoodTox

    regulatory · updated 2026-10-04

    Open →
  • EPA Chemical and Products Database

    exposure · updated September 2021

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA Inactive Ingredient Database

    regulatory · updated 2026-01-09

    Open →
  • FDA National Drug Code Directory

    regulatory · updated 2026-12-31

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • WHO JECFA Database

    regulatory · updated 2026-10-04

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →
Reference links (2)

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often EPA CPDat has listed Sodium chlorite in a product composition. These are source records, not Greenveil catalog products.

Source records

36

Named organisations

6

Laboratory suppliesConstruction and building materialsBatteriesSpecialty occupational productsCleaning and safetyPersonal care

Typical roles

Oral careOxidisingPreservativeAntimicrobial
See products using Sodium chlorite →

Catalog

Found in these products

Their ingredient lists include Sodium chlorite; each product's own rating depends on its whole formula, so it is shown on the product page, not here.