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  • cleaning
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Phytonadione [INCI], phytomenadione [INN]

CAS 84-80-0 · 100/100 · High conf.

Also registered as 5 other CAS numbers

11104-38-4 · 79083-00-4 · 10485-69-5 · 15973-57-6 · 50926-17-5

Phytonadione [INCI], phytomenadione [INN] chemical structure

Concern score

100/100Critical concern based on regulatory listings.
High confidence

Phytonadione [INCI], phytomenadione [INN] in plain language

What it is

On cosmetic ingredient lists it appears as “Phytonadione”.

Also known as Phytonadione · Phylloquinone e-form · Phytonadione, (e)- · Phylloquinone · Monodion · Phylloquinone, (e)-

Show all 28 names

Phytomenadione, (e)- · Synthex p · 2',3'-trans-Vitamin K1 · 2-Methyl-3-phytyl-1,4-naphthoquinone · 3-Phytylmenadione · Antihemorrhagic vitamin · Combinal K1 · Fitomenadiona · K-Ject · Kativ N · Kephton · Kinadion · Mephyton · Mono-Kay · Phyllochinon · Phylloquinone, K1 · Phytylmenadione · Trans-Phylloquinone · Vitamin K1 · alpha-Phylloquinone · phytomenadione · trans-vitamin K1

What it does

Used in consumer products as a conditioner.

  • Conditioner
Is it a concern?
Critical concern: no hazard classifications on record. It is banned in EU cosmetics.

Why it's flagged

Phytonadione [INCI], phytomenadione [INN] is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.

RestrictedEU EC — banned

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

Restrictions first, then routine listings from published regulatory sources.

  • In marketed US drugs
  • EU Annex II — prohibited
  • EU prohibited in cosmetics

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • Cleaning
  • Pharma
  • Food
  • Industrial

  • EUEC

    Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products.

    banned
    View source →
  • EUCosIngActiveCosmetics Regulation annex II / ref 1371.
    • Cosmetics Regulation annex II / ref 1371.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 41 composition records across product categories including Food and drug, Personal care, Raw materials. EPA CPDat classifies this chemical for functional uses including Softener and conditioner.
    • EPA CPDat observed this chemical in 41 composition records across product categories including Food and drug, Personal care, Raw materials. EPA CPDat classifies this chemical for functional uses including Softener and conditioner.Source →
  • USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 39 active drug products and 40 total products.
    • FDA NDC lists this ingredient in 39 active drug products and 40 total products.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Phytonadione [INCI], phytomenadione [INN]. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

  • JECFA

    Joint FAO/WHO Expert Committee on Food Additives

    No JECFA evaluation on file.

  • EFSA

    European Food Safety Authority

    No EFSA opinion on file.

Evidence & sources

No graded research studies for Phytonadione [INCI], phytomenadione [INN] yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

8 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →

  • EU CosIng Cosmetics Regulation Annexes

    regulatory · updated 2013-05-08

    Open →

  • EPA Chemical and Products Database

    exposure · updated September 2013

    Open →

  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →

  • FDA National Drug Code Directory

    regulatory · updated 2027-12-31

    Open →

  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →

  • openFDA Substance

    registry · updated 2026-05-24

    Open →

  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often EPA CPDat has listed Phytonadione [INCI], phytomenadione [INN] in a product composition. These are source records, not Greenveil catalog products.

Source records

41

Named organisations

6

Food and drugPersonal careRaw materials

Typical roles

Conditioner
See products using Phytonadione [INCI], phytomenadione [INN] →

Catalog

Found in these products

Their ingredient lists include Phytonadione [INCI], phytomenadione [INN]; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 1000+ →Find products without it →