beauty
cleaning
food
industrial

Calcium pantothenate

CAS 533-61-9 · 40/100 · High conf.

Also registered as 3 other CAS numbers

7693-16-5 · 138932-10-2 · 137-08-6

Concern score

40/100Moderate concern based on regulatory listings.

High confidence

Calcium pantothenate in plain language

What it is: Also known as Pantothenic acid calcium salt · Calcium D-pantothenate · (+)-pantothenic acid calcium salt · Calcium pantotenate · Calcium pantothenate, d- · D-ca pantothenate
Show all 32 names
D-calcium pantothenate · Pantothenic acid, calcium salt (2:1), d- · Vitamin B5, calcium salt · Bis(pantothenato)calcium · Calcium d-pantothenate (1:2) · Calcium pantothenate, (+)- · Ca-HOPA · Calcii pantothenas · Calcium d-Panthothenate · Calpan · Calpanate · Cris Pan · D-(+)-Pantothenic acid calcium salt · D-Pantothenic acid hemicalcium salt · Dextro calcium pantothenate · N-(2,4-Dihydroxy-3,3-dimethylbutyryl)-beta-alanine calcium · Pantholin · Pancal · Panthothenic acid hemicalcium salt · Pantothenate calcium · Pantothenate de calcium · calcium panthothenate · D-form calcium pantothenate · pantotenato de calcio · Pantothenic acid (as calcium pantothenate) · Pantothenic acid (as calcium)
What it does: Used in cosmetics as a skin-conditioning agent and a hair conditioner. Calcium Pantothenate is the calcium salt of pantothenic acid.
Skin conditioning
Hair conditioning
Flavouring
Conditioner
Antistatic
Is it a concern?: Moderate concern: no hazard classifications on record. It is listed for cosmetic use in the EU.

Why it's flagged

EPA CPDat observed this chemical in 330 composition records across product categories including Raw materials, Laboratory supplies, Personal care.

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

No restrictions found. Calcium pantothenate appears in these published regulatory listings.

In marketed US drugs

Recorded in these product areas

Found in consumer products
Beauty
Cleaning
Pharma
Food
Industrial

EUEFSAEFSA opinion2 entries
- Scientific Opinion on the safety and efficacy of pantothenic acid (calcium Dpantothenate and D-panthenol) as a feed additive for all animal species based on a dossier submitted by Lohmann Animal Health (EFSA FEEDAP)Source →
- Scientific Opinion on the safety and efficacy of pantothenic acid (calcium Dpantothenate and D-panthenol) as a feed additive for all animal species based on a dossier submitted by VITAC EEIG (EFSA FEEDAP)Source →
EUCosIngActiveCalcium Pantothenate is the calcium salt of pantothenic acid that conforms to the formula:
- Calcium Pantothenate is the calcium salt of pantothenic acid that conforms to the formula:Source →
USEPAcommercial use observedEPA CPDat observed this chemical in 330 composition records across product categories including Raw materials, Laboratory supplies, Personal care. EPA CPDat classifies this chemical for functional uses including Anti-static agent, Softener and conditioner, Pharmaceutical.
- EPA CPDat observed this chemical in 330 composition records across product categories including Raw materials, Laboratory supplies, Personal care. EPA CPDat classifies this chemical for functional uses including Anti-static agent, Softener and conditioner, Pharmaceutical.Source →
USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 14 active drug products and 19 total products.
- FDA NDC lists this ingredient in 14 active drug products and 19 total products.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
- openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

Independent scientific assessments cited by the records we hold, with the year and link where the record gives one.

SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.
EFSA
European Food Safety Authority
- Scientific Opinion on the safety and efficacy of pantothenic acid (calcium Dpantothenate and D-panthenol) as a feed additive for all animal species based on a dossier submitted by Lohmann Animal Health (EFSA FEEDAP)
  2011 · EU EFSA listing · Read the source →
- Scientific Opinion on the safety and efficacy of pantothenic acid (calcium Dpantothenate and D-panthenol) as a feed additive for all animal species based on a dossier submitted by VITAC EEIG (EFSA FEEDAP)
  2011 · EU EFSA listing · Read the source →

Evidence & sources

No graded research studies for Calcium pantothenate yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

8 data sources

Where this comes from

CosIng
regulatory · updated 2026-09-23
Open →
EFSA OpenFoodTox
regulatory · updated 2026-10-04
Open →
EPA Chemical and Products Database
exposure · updated September 2013
Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
Open →
FDA National Drug Code Directory
regulatory · updated 2027-12-31
Open →
FDA GSRS UNII
registry · updated 2026-02-26
Open →
openFDA Substance
registry · updated 2026-05-24
Open →
PubChem Live Enrichment
chemistry · updated 2026-05-17
Open →

Reference links (2)

Openfda substance

drugoffice.gov.hk

Read →

Openfda substance

labtests.info

Read →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often EPA CPDat has listed Calcium pantothenate in a product composition. These are source records, not Greenveil catalog products.

Source records

330

Named organisations

Raw materialsLaboratory suppliesPersonal careConstructionFood and drug

Typical roles

Skin conditioningHair conditioningFlavouringConditionerAntistatic

See products using Calcium pantothenate →

Catalog

Found in these products

Their ingredient lists include Calcium pantothenate; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 1000+ →Find products without it →

Co-occurrence

Often appears with

Ingredients that frequently appear alongside Calcium pantothenate in the catalog.