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Capsaicin

CAS 1217899-52-9

Also registered as 2 other CAS numbers

912457-62-6 · 404-86-4

Capsaicin chemical structure

Concern score

Not assessed — no hazard data yet.

Capsaicin in plain language

What it is

Also known as N-(4-HYDROXY-3-METHOXYBENZYL)-8-METHYL-6-NONENAMIDE · Ausanil · Axsain · Capzasin-hp · CNTX-4975 · Dolenon

Show all 29 names

Mioton · Ovocap · Ratden pe 40 · Togarashi orenji · Trans-capsaicin · Zostrix · (E)-8-METHYL-N-VANILLYL-6-NONENAMIDE · Algrx 4975 · Adlea · Capsaicine · Capsicin · Chilli Orange · Isodecenoic acid vanillylamide · NCI-C56564 · NGX-1998 · NGX-4010 · Qutenza · Styptysat · capsaicin (correct percentage from label) · capsaicin 0.025% · oleoresin capsicum · trans-8-Methyl-N-vanillyl-6-nonenamide · Capsaicin (constituent of capsicum)

What it does

Used in cosmetics as a skin-conditioning agent and a fragrance ingredient.

  • Skin conditioning
  • Fragrance
  • Flavouring
  • Conditioner
  • Deodorant
Is it a concern?
We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

Regulation

No restrictions found. Capsaicin appears in these published regulatory listings.

  • In marketed US drugs

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • Pharma
  • Food
  • EUCosIngActiveListed in CosIng inventory for cosmetic use.
    • Listed in CosIng inventory for cosmetic use.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 25 composition records across product categories including Pesticides, Construction and building materials, Personal care. EPA CPDat classifies this chemical for functional uses including Deodorizer, Softener and conditioner, Fragrance.
    • EPA CPDat observed this chemical in 25 composition records across product categories including Pesticides, Construction and building materials, Personal care. EPA CPDat classifies this chemical for functional uses including Deodorizer, Softener and conditioner, Fragrance.Source →
  • USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 187 active drug products and 188 total products.
    • FDA NDC lists this ingredient in 187 active drug products and 188 total products.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Capsaicin. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Capsaicin yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

7 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EPA Chemical and Products Database

    exposure · updated May 2008

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA National Drug Code Directory

    regulatory · updated 2027-12-31

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →
Reference links (2)
Openfda substance

accessdata.fda.gov

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.

Fragrance avoidance

Not a strong fit for fragrance avoidance because it carries Fragrance.

Avoid

The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.

Where it has been recorded

How often FDA National Drug Code directory has listed Capsaicin in a product composition. These are source records, not Greenveil catalog products.

Source records

188

Typical roles

Skin conditioningFragranceFlavouringConditionerDeodorant
See products using Capsaicin →

Catalog

Found in these products

Their ingredient lists include Capsaicin; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

Co-occurrence

Often appears with

Ingredients that frequently appear alongside Capsaicin in the catalog.