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Pantothenic acid

CAS 3563-85-7 · 40/100 · High conf.

Also registered as 3 other CAS numbers

1803316-48-4 · 2087491-31-2 · 79-83-4

Pantothenic acid chemical structure

Concern score

40/100Moderate concern based on regulatory listings.
High confidence

Pantothenic acid in plain language

What it is

Also known as Vitamin B5 · Chick antidermatitis factor · Pantothenic acid (d) · Vitamin B-5 · (+)-Pantothenic acid · (D)-(+)-Pantothenic acid

Show all 19 names

B 5, Vitamin · Calc pantoth · Cantopal · D(+)-N-(2,4-Dihydroxy-3,3-dimethylbutyryl)-beta-alanine · D-Pantothenic acid · Kyselina pantothenova · N-(2,4-Dihydroxy-3,3-dimethylbutyryl)-beta-alanine · Pantothenate · Panthothenic acid · Zinc Pantothenate · Pantothenic acid, D- · vitamin b3 · β-Alanine, N-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)-, (R)-

What it does

Used in cosmetics as a skin-conditioning agent, a hair conditioner and an antistatic agent.

  • Skin conditioning
  • Hair conditioning
  • Antistatic
  • Conditioner
Is it a concern?
Moderate concern: no hazard classifications on record. It is listed for cosmetic use in the EU.

Why it's flagged

EPA CPDat observed this chemical in 286 composition records across product categories including Personal care.

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

No restrictions found. Pantothenic acid appears in these published regulatory listings.

  • In marketed US drugs

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • Cleaning
  • EUCosIngActiveListed in CosIng inventory for cosmetic use.
    • Listed in CosIng inventory for cosmetic use.Source →
  • EUEFSAEFSA opinionScientific Opinion on Dietary Reference Values for pantothenic acid (EFSA NDA)
    • Scientific Opinion on Dietary Reference Values for pantothenic acid (EFSA NDA)Source →
  • EUEFSAReport from international authorityOpinion of the Scientific Committee on Food on the Tolerable Upper Intake Level of Pantothenic Acid (SCF)
    • Opinion of the Scientific Committee on Food on the Tolerable Upper Intake Level of Pantothenic Acid (SCF)Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 286 composition records across product categories including Personal care. EPA CPDat classifies this chemical for functional uses including Anti-static agent, Softener and conditioner.
    • EPA CPDat observed this chemical in 286 composition records across product categories including Personal care. EPA CPDat classifies this chemical for functional uses including Anti-static agent, Softener and conditioner.Source →
  • USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 39 active drug products and 53 total products.
    • FDA NDC lists this ingredient in 39 active drug products and 53 total products.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

Independent scientific assessments cited by the records we hold, with the year and link where the record gives one.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

  • EFSA

    European Food Safety Authority

    • Scientific Opinion on Dietary Reference Values for pantothenic acid (EFSA NDA)

      2014 · EU EFSA listing · Read the source →

    • Opinion of the Scientific Committee on Food on the Tolerable Upper Intake Level of Pantothenic Acid (SCF)

      2002 · EU EFSA listing · Read the source →

Evidence & sources

No graded research studies for Pantothenic acid yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

8 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EFSA OpenFoodTox

    regulatory · updated 2026-10-04

    Open →
  • EPA Chemical and Products Database

    exposure · updated September 2018

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA National Drug Code Directory

    regulatory · updated 2030-01-07

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often EPA CPDat has listed Pantothenic acid in a product composition. These are source records, not Greenveil catalog products.

Source records

286

Named organisations

6

Personal care

Typical roles

Skin conditioningHair conditioningAntistaticConditioner
See products using Pantothenic acid →

Catalog

Found in these products

Their ingredient lists include Pantothenic acid; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

Co-occurrence

Often appears with

Ingredients that frequently appear alongside Pantothenic acid in the catalog.