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  1. Ingredients
  2. pharma
  3. Poloxamer 407
  • pharma

Poloxamer 407

CAS 691397-13-4

Concern score

Not assessed — no hazard data yet.

Why it's flagged

Route: INTRATYMPANIC; Dosage form: SUSPENSION; Maximum daily exposure: 63 mg

Regulation

No restrictions found. Poloxamer 407 appears in these published regulatory listings.

  • definition_level:incomplete
  • definition_type:primary
  • inactive_ingredient_database
  • ingredient_type:ingredient substance
  • substance_class:polymer
  • substance_type:polymer
  • USFDAinactive ingredient database15 entries — 5 administration routes
    • Route: INTRATYMPANIC; Dosage form: SUSPENSION; Maximum daily exposure: 63 mgSource →
    • Route: OPHTHALMIC; Dosage form: GEL; Maximum daily exposure: 1 mgSource →
    • Route: OPHTHALMIC; Dosage form: SOLUTION; Potency: 0.2 %w/vSource →
    • Route: OPHTHALMIC; Dosage form: SUSPENSION/ DROPS; Maximum daily exposure: 1 mgSource →
    • Route: ORAL; Dosage form: CAPSULE; Maximum daily exposure: 468 mgSource →
    • Route: ORAL; Dosage form: CAPSULE, DELAYED RELEASE; Maximum daily exposure: 5 mgSource →
    • Route: ORAL; Dosage form: CAPSULE, EXTENDED RELEASE; Maximum daily exposure: 40 mgSource →
    • Route: ORAL; Dosage form: POWDER, FOR SUSPENSION; Potency: 0.01 mgSource →
    • Route: ORAL; Dosage form: SOLUTION; Potency: 50 mg/5mlSource →
    • Route: ORAL; Dosage form: SUSPENSION; Maximum daily exposure: 10 mgSource →
    • Route: ORAL; Dosage form: TABLET; Maximum daily exposure: 495 mgSource →
    • Route: PERIODONTAL; Dosage form: GEL; Potency: 155 mgSource →
    • Route: TOPICAL; Dosage form: CREAM; Maximum daily exposure: 13 mgSource →
    • Route: TOPICAL; Dosage form: GEL; Maximum daily exposure: 28 mgSource →
    • Route: TOPICAL; Dosage form: LOTION; Potency: 1 %w/wSource →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as polymer.
    • openFDA substance registry classifies this ingredient as polymer.Source →

Evidence

No graded sources yet for Poloxamer 407. We publish evidence only once a source is linked and reviewed — this ingredient is in the catalog, but has not been assessed.

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Catalog

Found in these products

102 products
  • Cclear C
    shampooclear · Open Beauty FactsCritical
  • OBoral b OB
    oralboral b · Non Food ProductsModerate
  • CColgate C
    MundspülungColgateMinor
  • CPCOLGATE PALMOLIVE NORGE AS CP
    Colgate Munnskyll Blå 250mlCOLGATE PALMOLIVE NORGE AS · Non Food ProductsCritical
  • LListerine L
    MundspülungListerineHigh
  • GGreenveil G
    listerine cool
  • CCrest C
    Crest+scope completeCrest · Toothpaste
  • AAct A
    Wild Watermelon RinseAct · Non Food ProductsCritical
  • GGreenveil G
    Listerine cool mintCritical
  • TTheraBreath T
    MouthwashTheraBreath
  • FAFOODBROKER AS FA
    Listerine Mouthwash Total Care 1lFOODBROKER AS · Non Food ProductsMinor
  • LListerine L
    Gum Treatment MouthwashListerine · Gum TreatmentHigh
  • LListerine L
    MouthwashListerine · MouthwashCritical
  • LListerine L
    Total Care Stay White MouthwashListerine · Non Food ProductsCritical
  • CPCOLGATE PALMOLIVE NORGE AS CP
    Colgate Tannkrem Active Fresh 75mlCOLGATE PALMOLIVE NORGE AS · Non Food ProductsCritical
  • ECElmex, Colgate-Palmolive EC
    Elmex Sensitive Professional Repair & Prevent TandpastaElmex, Colgate-Palmolive · Gevoelige TandenHigh
  • UUltrex,Unilever U
    Champú cítrico anticaspa cabello grasoUltrex,Unilever · HairHigh
  • GGreenveil G
    Arm & Hammer TheraBreathCritical
  • GGreenveil G
    actHigh
  • GGreenveil G
    act restoring mouth washHigh
  • GGreenveil G
    benadrylHigh
  • BCbasic care BC
    basic care night time sleep aidbasic care · DrugCritical
  • GGreenveil G
    helloHigh
  • LListerine L
    listerine total careListerine · Non Food ProductsModerate

Co-occurrence

Often appears with

Ingredients that frequently appear alongside Poloxamer 407 in the catalog.

  • Poloxamer 124Co occurs