TartrazineSouthampton study link to hyperactivity/attention effects in children; can trigger reactions in sensitive individuals.
Sunset yellow FCFSouthampton Six colour; hyperactivity/attention concern in children.
Titanium dioxidePossible genotoxicity (DNA/chromosomal damage) could not be ruled out; no longer considered safe as a food additive.
DiphosphatesInorganic phosphate additives are highly bioavailable; high additive-phosphate intake is associated with increased cardiovascular and kidney burden, particularly in chronic kidney disease.
Carboxymethyl cellulose (CMC)Synthetic emulsifier linked in animal and in-vitro studies to gut-microbiome disruption and intestinal inflammation; human evidence is emerging.
Per-ingredient concern · chemical identity, not food safety