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Water-soluble zinc salts with the exception of zinc 4- hydroxy-benzene sulphonate (entry 25 of Annex III)

CAS 557-34-6 · 70/100 · High conf.

Also registered as 12 other CAS numbers

57130-83-3 · 57130-85-5 · 223776-82-7 · 2319654-25-4 · 546-46-3 · 1949-15-1 · 4468-02-4 · 5970-45-6 · 7446-19-7 · 7446-20-0 · 7646-85-7 · 7733-02-0

Water-soluble zinc salts with the exception of zinc 4- hydroxy-benzene sulphonate (entry 25 of Annex III) chemical structure

Concern score

70/100High concern based on regulatory listings.

High confidence

Water-soluble zinc salts with the exception of zinc 4- hydroxy-benzene sulphonate (entry 25 of Annex III) in plain language

What it is: On cosmetic ingredient lists it appears as “Lactobacillus lac/calcium/phosphorous/magnesium/zinc ferment”.
Also known as Lactobacillus lac/calcium/phosphorous/magnesium/zinc ferment · Porphyridium/zinc ferment · Zinc acetate · Zinc aspartate · Zinc borate · Zinc chloride
Show all 40 names
Zinc citrate · Zinc dibutyldithiocarbamate · Zinc glucoheptonate · Zinc gluconate · Zinc glutamate · Zinc lactate · Zinc sulfate · Zinc Sulphate · Zinc sulfate heptahydrate · Zinc sulfate hydrate · anhydrous Zinc chloride · Zinc sulphate heptahydrate · Zinc sulphate monohydrate · Sulfuric acid, zinc salt (1:1), heptahydrate · Zinc sulfate (1:1) heptahydrate · Zinc sulphate (1:1) heptahydrate · Zinc sulfate--water (1/1/7) · Sulfato de zinc · Trizinc dicitrate · UNII-N57JI2K7WP · White vitriol (heptahydrate) · Zinc sulfate (heptahydrate) · Zinksulfat-heptahydrat · Zinc di(acetate) · Zinc sulfate (ZnSO4) heptahydrate · Zinc sulfate hydrate (1:1:7) · Zinc vitriol (heptahydrate) · Zincsulfateheptahydrate · ZnSO4.7H2O · bis(D-Gluconato-O1,O2)zinc · zinc sulfate heptahydrate (1:1:7) · zinci chloridum · zinci sulfas · Zincum sulphuricum
What it does: Used in cosmetics as an antimicrobial, a skin-conditioning agent and an antiplaque. Zinc Acetate is the zinc salt of acetic acid.
Antimicrobial
Skin conditioning
Antiplaque
Astringent
Deodorant
Hair conditioning
Is it a concern?: High concern: no hazard classifications on record. It is restricted in EU cosmetics.

Why it's flagged

Water-soluble zinc salts with the exception of zinc 4- hydroxy-benzene sulphonate (entry 25 of Annex III) is restricted in cosmetic products under Annex III of the EU Cosmetics Regulation (EC) 1223/2009.

RestrictedEU EC — restricted

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

Restrictions first, then routine listings from published regulatory sources.

In marketed US drugs
EU Annex III — restricted
EU restricted in cosmetics

Recorded in these product areas

Found in consumer products
Pharma
Food
Industrial

EUEC
Annex III of EU Cosmetics Regulation (EC) 1223/2009: substances which cosmetic products must not contain except subject to the restrictions laid down. Product types: (a) Toothpaste intended for users above 1 year of age (b) Toothpaste intended for children between 6 months and 1 year of age (c) Mouthwash intended for users above 6 years of age (d) Other products Maximum concentration: (a) 1 % (as zinc) (b) 0,72 % (as zinc) (c) 0,1 % (as zinc) (d) 1 % (as zinc)
restricted
View source →

EUCosIngActive7 entries
- Cosmetics Regulation annex III / ref 24.Source →
- Zinc Acetate is the zinc salt of acetic acid that conforms to the formula: Restriction: III/24Source →
- Zinc Chloride is the inorganic salt that conforms to the formula: Restriction: III/24Source →
- Zinc Citrate is the zinc salt of citric acid that conforms to the formula: Restriction: III/24Source →
- Zinc Gluconate is the zinc salt of gluconic acid that conforms to the formula: Restriction: III/24Source →
- Restriction: III/24Source →
- Zinc Sulfate is the inorganic salt that conforms to the formula: Restriction: III/24Source →
EUEFSAEFSA opinion3 entries
- Scientific Opinion on the safety and efficacy of zinc compounds (E6) as feed additives for all animal species (zinc acetate, dihydrate; zinc chloride, anhydrous; zinc oxide; zinc sulphate, heptahydrate; zinc sulphate, monohydrate; zinc chelate of amino acids, hydrate; zinc chelate of glycine, hydrate), based on a dossier submitted by FEFANA asbl (EFSA FEEDAP)Source →
- Scientific Opinion on safety and efficacy of zinc compounds (E6) as feed additive for all species: zinc sulphate monohydrate, based on a dossier submitted by Grillo-Werke AG/EMFEMA (EFSA FEEDAP)Source →
- Scientific Opinion on safety and efficacy of zinc compounds (E6) as feed additives for all animal species: Zinc sulphate monohydrate, based on a dossier submitted by Helm AG (EFSA FEEDAP)Source →
USEPAcommercial use observedEPA CPDat observed this chemical in 49 composition records across product categories including Food and drug, Arts and crafts/office supplies, Laboratory supplies. EPA CPDat classifies this chemical for functional uses including process regulator, Flavouring and nutrient, Dye.
- EPA CPDat observed this chemical in 49 composition records across product categories including Food and drug, Arts and crafts/office supplies, Laboratory supplies. EPA CPDat classifies this chemical for functional uses including process regulator, Flavouring and nutrient, Dye.Source →
USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 16 active drug products and 17 total products.
- FDA NDC lists this ingredient in 16 active drug products and 17 total products.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
- openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

Independent scientific assessments cited by the records we hold, with the year and link where the record gives one.

SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.
EFSA
European Food Safety Authority
- Scientific Opinion on the safety and efficacy of zinc compounds (E6) as feed additives for all animal species (zinc acetate, dihydrate; zinc chloride, anhydrous; zinc oxide; zinc sulphate, heptahydrate; zinc sulphate, monohydrate; zinc chelate of amino acids, hydrate; zinc chelate of glycine, hydrate), based on a dossier submitted by FEFANA asbl (EFSA FEEDAP)
  2015 · EU EFSA listing · Read the source →
- Scientific Opinion on safety and efficacy of zinc compounds (E6) as feed additive for all species: zinc sulphate monohydrate, based on a dossier submitted by Grillo-Werke AG/EMFEMA (EFSA FEEDAP)
  2012 · EU EFSA listing · Read the source →
- Scientific Opinion on safety and efficacy of zinc compounds (E6) as feed additives for all animal species: Zinc sulphate monohydrate, based on a dossier submitted by Helm AG (EFSA FEEDAP)
  2012 · EU EFSA listing · Read the source →

Evidence & sources

No graded research studies for Water-soluble zinc salts with the exception of zinc 4- hydroxy-benzene sulphonate (entry 25 of Annex III) yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

9 data sources

Where this comes from

CosIng
regulatory · updated 2026-09-23
Open →
EU CosIng Cosmetics Regulation Annexes
regulatory · updated 2026-04-28
Open →
EFSA OpenFoodTox
regulatory · updated 2026-10-04
Open →
EPA Chemical and Products Database
exposure · updated January 7, 2008
Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
Open →
FDA National Drug Code Directory
regulatory · updated 2026-12-31
Open →
FDA GSRS UNII
registry · updated 2026-02-26
Open →
openFDA Substance
registry · updated 2026-05-24
Open →
PubChem Live Enrichment
chemistry · updated 2026-05-17
Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often EPA CPDat has listed Water-soluble zinc salts with the exception of zinc 4- hydroxy-benzene sulphonate (entry 25 of Annex III) in a product composition. These are source records, not Greenveil catalog products.

Source records

Named organisations

Food and drugArts and crafts/office suppliesLaboratory supplies

Typical roles

AntimicrobialSkin conditioningAntiplaqueAstringentDeodorantHair conditioning

See products using Water-soluble zinc salts with the exception of zinc 4- hydroxy-benzene sulphonate (entry 25 of Annex III) →

Catalog

Found in these products

Their ingredient lists include Water-soluble zinc salts with the exception of zinc 4- hydroxy-benzene sulphonate (entry 25 of Annex III); each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 1000+ →Find products without it →

Co-occurrence

Often appears with

Ingredients that frequently appear alongside Water-soluble zinc salts with the exception of zinc 4- hydroxy-benzene sulphonate (entry 25 of Annex III) in the catalog.