Is PROPYLENE GLYCOL Safe? — Ingredient Safety Profile · Greenveil
Ingredients PROPYLENE GLYCOL beauty / cleaning / industrial / pharma
PROPYLENE GLYCOL EPA CPDat observed this chemical in 16177 composition records across product categories including Cleaning and safety, Construction and building materials, Raw materials.
Research docs 0 Claims 0 Sources 88 Function Anti-freeze agent • Biocide Identifier DTXSID0021206 45
Concern score
45/100 Moderate concern based on regulatory listings.
How we scored this The concern value is driven by the published classifications and regulatory status below — not by a single signal.
Concern score 45/100 (moderate) · high confidence.
Where it appears Prevalence of PROPYLENE GLYCOL in our catalog (epa_cpdat).
Cleaning and safety Construction and building materials Raw materials Furniture and furnishings Cons. electronics, mech. appliances, and machinery Home maintenance
Typical roles
Anti-freeze agent Biocide Delivery vehicle Fragrance Humectant
Suitability Context-specific fit derived from published classifications and the current ingredient evidence profile.
Food use
Food-use source coverage is present in the current record.
The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.
Fragrance avoidance
Not a strong fit for fragrance avoidance because it carries Fragrance.
Linked research Primary documents currently linked to this ingredient record.
No linked research documents are attached to this ingredient yet.
Extracted claims Structured claim signals pulled from linked ingredient research.
No extracted claims are attached to this ingredient yet.
Regulatory status Published jurisdiction-level classifications and regulatory designations for this ingredient.
EPA CPDat observed this chemical in 16177 composition records across product categories including Cleaning and safety, Construction and building materials, Raw materials. EPA CPDat classifies this chemical for functional uses including Solvent, Stabilizing agent, Humectant.
inactive ingredient database Route: AURICULAR (OTIC); Dosage form: SOLUTION; Potency: 56.55 %w/v
inactive ingredient database Preservative
Processing aids not otherwise specified
Softener and conditioner
The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.
Evidence read The published evidence profile currently shaping this ingredient record.
No evidence profiles are attached to this ingredient yet.
Route: AURICULAR (OTIC); Dosage form: SOLUTION/ DROPS; Potency: ADJ PH
inactive ingredient database Route: AURICULAR (OTIC); Dosage form: SUSPENSION; Potency: 10 %w/v
inactive ingredient database Route: BUCCAL; Dosage form: FILM; Potency: 1.48 mg
inactive ingredient database Route: BUCCAL; Dosage form: FILM, SOLUBLE; Maximum daily exposure: 5 mg
inactive ingredient database Route: DENTAL; Dosage form: OINTMENT; Potency: NA
inactive ingredient database Route: DENTAL; Dosage form: PASTE; Potency: 0.5 %w/w
inactive ingredient database Route: DENTAL; Dosage form: SOLUTION; Potency: 2 %w/w
inactive ingredient database Route: INTRAMUSCULAR; Dosage form: INJECTION; Maximum daily exposure: 7459 mg
inactive ingredient database Route: INTRAMUSCULAR; Dosage form: INJECTION, SOLUTION; Maximum daily exposure: 4000 mg
inactive ingredient database Route: INTRAVENOUS; Dosage form: INJECTION; Maximum daily exposure: 16624 mg
inactive ingredient database Route: INTRAVENOUS; Dosage form: INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION; Potency: 63.4 %w/v
inactive ingredient database Route: INTRAVENOUS; Dosage form: INJECTION, SOLUTION; Maximum daily exposure: 4000 mg
inactive ingredient database Route: INTRAVENOUS; Dosage form: SOLUTION; Potency: 5 %w/v
inactive ingredient database Route: INTRAVENOUS; Dosage form: SOLUTION, CONCENTRATE; Potency: 50.33 %w/v
inactive ingredient database Route: NASAL; Dosage form: SPRAY; Maximum daily exposure: 5 mg
inactive ingredient database Route: NASAL; Dosage form: SPRAY, METERED; Maximum daily exposure: 240 mg
inactive ingredient database Route: OPHTHALMIC; Dosage form: EMULSION; Potency: 1.5 %w/v
inactive ingredient database Route: OPHTHALMIC; Dosage form: GEL; Potency: 0.44 %w/w
inactive ingredient database Route: OPHTHALMIC; Dosage form: SOLUTION; Potency: 1 %w/v
inactive ingredient database Route: OPHTHALMIC; Dosage form: SOLUTION/ DROPS; Potency: 0.75 %w/v
inactive ingredient database Route: OPHTHALMIC; Dosage form: SUSPENSION; Potency: 0.6 %w/v
inactive ingredient database Route: OPHTHALMIC; Dosage form: SUSPENSION/ DROPS; Potency: 0.75 %w/v
inactive ingredient database Route: ORAL; Dosage form: CAPSULE; Maximum daily exposure: 1072 mg
inactive ingredient database Route: ORAL; Dosage form: CAPSULE, COATED; Potency: 25 mg
inactive ingredient database Route: ORAL; Dosage form: CAPSULE, COATED, EXTENDED RELEASE; Potency: NA
inactive ingredient database Route: ORAL; Dosage form: CAPSULE, DELAYED RELEASE; Potency: 1.7 mg
inactive ingredient database Route: ORAL; Dosage form: CAPSULE, EXTENDED RELEASE; Maximum daily exposure: 8 mg
inactive ingredient database Route: ORAL; Dosage form: CAPSULE, LIQUID FILLED; Maximum daily exposure: 42 mg
inactive ingredient database Route: ORAL; Dosage form: CONCENTRATE; Maximum daily exposure: 7000 mg
inactive ingredient database Route: ORAL; Dosage form: DROPS; Potency: 200 mg/1ml
inactive ingredient database Route: ORAL; Dosage form: ELIXIR; Maximum daily exposure: 9306 mg
inactive ingredient database Route: ORAL; Dosage form: LIQUID; Maximum daily exposure: 29008 mg
inactive ingredient database Route: ORAL; Dosage form: SOLUTION; Maximum daily exposure: 22602 mg
inactive ingredient database Route: ORAL; Dosage form: SOLUTION, CONCENTRATE; Maximum daily exposure: 2590 mg
inactive ingredient database Route: ORAL; Dosage form: SUSPENSION; Maximum daily exposure: 27120 mg
inactive ingredient database Route: ORAL; Dosage form: SUSPENSION, EXTENDED RELEASE; Maximum daily exposure: 1000 mg
inactive ingredient database Route: ORAL; Dosage form: SYRUP; Maximum daily exposure: 5700 mg
inactive ingredient database Route: ORAL; Dosage form: TABLET; Maximum daily exposure: 64 mg
inactive ingredient database Route: ORAL; Dosage form: TABLET, COATED; Maximum daily exposure: 16 mg
inactive ingredient database Route: ORAL; Dosage form: TABLET, DELAYED RELEASE; Maximum daily exposure: 36 mg
inactive ingredient database Route: ORAL; Dosage form: TABLET, EXTENDED RELEASE; Potency: 9 mg
inactive ingredient database Route: ORAL; Dosage form: TABLET, FILM COATED; Maximum daily exposure: 96 mg
inactive ingredient database Route: ORAL; Dosage form: TABLET, FILM COATED, EXTENDED RELEASE; Maximum daily exposure: 19 mg
inactive ingredient database Route: RECTAL; Dosage form: AEROSOL, FOAM; Maximum daily exposure: 1214 mg
inactive ingredient database Route: RECTAL; Dosage form: AEROSOL, METERED; Potency: NA
inactive ingredient database Route: RECTAL; Dosage form: GEL; Maximum daily exposure: 3315 mg
inactive ingredient database Route: RECTAL; Dosage form: OINTMENT; Maximum daily exposure: 27 mg
inactive ingredient database Route: RECTAL; Dosage form: SUSPENSION; Maximum daily exposure: 90400 mg
inactive ingredient database Route: RESPIRATORY (INHALATION); Dosage form: LIQUID; Potency: 10 %w/w
inactive ingredient database Route: RESPIRATORY (INHALATION); Dosage form: SOLUTION; Potency: 25 %w/w
inactive ingredient database Route: SUBCUTANEOUS; Dosage form: INJECTION; Potency: 1.4 %w/v
inactive ingredient database Route: SUBCUTANEOUS; Dosage form: INJECTION, SOLUTION; Potency: 1.4 %w/v
inactive ingredient database Route: SUBLINGUAL; Dosage form: SPRAY; Maximum daily exposure: 36 mg
inactive ingredient database Route: TOPICAL; Dosage form: AEROSOL; Potency: 19.2 %w/w
inactive ingredient database Route: TOPICAL; Dosage form: AEROSOL, FOAM; Maximum daily exposure: 1800 mg
inactive ingredient database Route: TOPICAL; Dosage form: CLOTH; Potency: 0.03 mg/mg
inactive ingredient database Route: TOPICAL; Dosage form: CREAM; Maximum daily exposure: 6113 mg
inactive ingredient database Route: TOPICAL; Dosage form: CREAM, AUGMENTED; Potency: 8 %w/w
inactive ingredient database Route: TOPICAL; Dosage form: EMULSION; Potency: 8 %w/w
inactive ingredient database Route: TOPICAL; Dosage form: GEL; Maximum daily exposure: 4522 mg
inactive ingredient database Route: TOPICAL; Dosage form: GEL, METERED; Maximum daily exposure: 1225 mg
inactive ingredient database Route: TOPICAL; Dosage form: JELLY; Potency: 20 %w/w
inactive ingredient database Route: TOPICAL; Dosage form: LOTION; Maximum daily exposure: 3392 mg
inactive ingredient database Route: TOPICAL; Dosage form: LOTION, AUGMENTED; Maximum daily exposure: 2070 mg
inactive ingredient database Route: TOPICAL; Dosage form: OINTMENT; Maximum daily exposure: 5148 mg
inactive ingredient database Route: TOPICAL; Dosage form: OINTMENT, AUGMENTED; Maximum daily exposure: 714 mg
inactive ingredient database Route: TOPICAL; Dosage form: SHAMPOO; Potency: 8 %w/w
inactive ingredient database Route: TOPICAL; Dosage form: SHAMPOO, SUSPENSION; Potency: 2 %w/w
inactive ingredient database Route: TOPICAL; Dosage form: SOLUTION; Maximum daily exposure: 4886 mg
inactive ingredient database Route: TOPICAL; Dosage form: SPONGE; Potency: 40 %w/w
inactive ingredient database Route: TOPICAL; Dosage form: SUSPENSION; Potency: 5.28 %w/v
inactive ingredient database Route: TOPICAL; Dosage form: SUSPENSION/ DROPS; Potency: 0.75 %w/v
inactive ingredient database Route: TOPICAL; Dosage form: SWAB; Potency: 34.6 %w/w
inactive ingredient database Route: TOPICAL; Dosage form: SYSTEM; Maximum daily exposure: 4200 mg
inactive ingredient database Route: TRANSDERMAL; Dosage form: FILM, EXTENDED RELEASE; Potency: 58.13 mg
inactive ingredient database Route: TRANSDERMAL; Dosage form: GEL; Maximum daily exposure: 500 mg
inactive ingredient database Route: VAGINAL; Dosage form: AEROSOL, FOAM; Potency: 6.4 %w/w
inactive ingredient database Route: VAGINAL; Dosage form: CREAM; Maximum daily exposure: 1225 mg
inactive ingredient database Route: VAGINAL; Dosage form: GEL; Maximum daily exposure: 750 mg
inactive ingredient database Route: VAGINAL; Dosage form: SUPPOSITORY; Potency: 252 mg
inactive ingredient database Route: VAGINAL; Dosage form: TAMPON; Potency: 62.1 mg
FDA NDC lists this ingredient in 97 active drug products and 114 total products.
listed in openFDA substance openFDA substance registry classifies this ingredient as chemical.
