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Cyclodextrin

CAS 100091-36-9 · 20/100 · High conf.

Also registered as 5 other CAS numbers

131076-21-6 · 856575-11-6 · 1011498-90-0 · 7585-39-9 · 12619-70-4

Concern score

20/100Minor concern based on regulatory listings.
High confidence

Cyclodextrin in plain language

What it is

Also known as Beta-cyclodextrin · Cyclodextrins · Cavasol W 7M-TL · Celdex · Celdex CH 20 · Celdex CH 30

Show all 11 names

Celdex SH 20 · Celdex SH 40 · Celdex SL 20 · Celdex TB 50 · Cycloheptapentylose

What it does

Used in cosmetics as an absorbent and a chelating agent.

  • Absorbent
  • Chelating
  • Chelating agent
  • Deodorant
Is it a concern?
Minor concern: no hazard classifications on record. It is listed for cosmetic use in the EU.

Why it's flagged

EFSA OpenFoodTox genotoxicity classification: Negative. Source: EFSA ANS 2016

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

No restrictions found. Cyclodextrin appears in these published regulatory listings.

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • Cleaning
  • EUCosIngActiveListed in CosIng inventory for cosmetic use.
    • Listed in CosIng inventory for cosmetic use.Source →
  • EUEFSAEFSA opinionRe-evaluation of Beta-cyclodextrin (E 459) as a food additive (EFSA ANS)
    • Re-evaluation of Beta-cyclodextrin (E 459) as a food additive (EFSA ANS)Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 375 composition records across product categories including Personal care, Cleaning products and household care. EPA CPDat classifies this chemical for functional uses including Deodorizer, Absorbent, Chelating agent.
    • EPA CPDat observed this chemical in 375 composition records across product categories including Personal care, Cleaning products and household care. EPA CPDat classifies this chemical for functional uses including Deodorizer, Absorbent, Chelating agent.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as mixture.
    • openFDA substance registry classifies this ingredient as mixture.Source →

Expert safety opinions

Independent scientific assessments cited by the records we hold, with the year and link where the record gives one.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

  • EFSA

    European Food Safety Authority

    • Re-evaluation of Beta-cyclodextrin (E 459) as a food additive (EFSA ANS)

      2016 · EU EFSA listing · Read the source →

Evidence & sources

No graded research studies for Cyclodextrin yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

6 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →

  • EFSA OpenFoodTox

    regulatory · updated 2026-10-02

    Open →

  • EPA Chemical and Products Database

    exposure · updated September 2018

    Open →

  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →

  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →

  • openFDA Substance

    registry · updated 2026-05-24

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often EPA CPDat has listed Cyclodextrin in a product composition. These are source records, not Greenveil catalog products.

Source records

375

Named organisations

6

Personal careCleaning products and household care

Typical roles

AbsorbentChelatingChelating agentDeodorant
See products using Cyclodextrin →

Catalog

Found in these products

Their ingredient lists include Cyclodextrin; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 96 →Find products without it →