What does Sodium phosphate, dibasic, anhydrous do?

Used in cosmetics as an anticorrosive, a pH buffer and a fragrance ingredient.

Is Sodium phosphate, dibasic, anhydrous safe?

We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

beauty
cleaning
food
industrial

Sodium phosphate, dibasic, anhydrous

CAS 148560-76-3

Also registered as 3 other CAS numbers

1374442-71-3 · 7558-79-4 · 7782-85-6

Sodium phosphate, dibasic, anhydrous chemical structure

Concern score

Not assessed — no hazard data yet.

Sodium phosphate, dibasic, anhydrous in plain language

What it is: On cosmetic ingredient lists it appears as “Disodium phosphate”.
Also known as Disodium phosphate · Sodium phosphate dibasic · Sodium phosphate · Dibasic anhydrous sodium phosphate · Dibasic sodium phosphate · Sodium phosphate,dibasic,anhydrous
Show all 37 names
Disodium acid phosphate · Disodium hydrogen phosphate · Secondary sodium phosphate · Acetest · Dibasic sodium phosphate anhydrous · Disodium hydrogen phosphate anhydrous · Anhydrous disodium phosphate · Exsiccated sodium phosphate · Phosphoric acid, disodium salt, anhydrous · Phosphoric acid, sodium salt (1:2) · Sodium monohydrogen phosphate · Anhydrous sodium acid phosphate · Caswell No. 778 · Disodium hydrogen monophosphate · Dinatriumhydrogenorthophosphat · Disodium acid orthophosphate · Disodium hydrogenorthophosphate · Disodium orthophosphate · E-339(II) · Ins NO.339(II) · INS-339(II) · Natriumphosphat · Phosphate of soda · disodium salt Phosphoric acid · Soda phosphate · Sodium hydrogen phosphate · dinatrii phosphas · disodium hydrogenphosphate · disodium phosphate. (no mfr cas# provided) · Osmoprep component sodium phosphate, dibasic anhydrous · Visicol component sodium phosphate, dibasic anhydrous
What it does: Used in cosmetics as an anticorrosive, a pH buffer and a fragrance ingredient.
Anticorrosive
Buffering
Fragrance
Texturizer, thickener, acidity regulator, emulsifier
Chelating agent
pH adjuster
Is it a concern?: We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

Regulation

No restrictions found. Sodium phosphate, dibasic, anhydrous appears in these published regulatory listings.

In marketed US drugs
Inactive ingredient in US drugs

Recorded in these product areas

Found in consumer products
Beauty
Cleaning
Pharma
Food
Industrial

USFDAinactive ingredient database48 entries — 17 administration routes
- Route: INTRALESIONAL; Dosage form: INJECTION; Maximum daily exposure: 28 mgSource →
- Route: INTRALESIONAL; Dosage form: INJECTION, SUSPENSION; Maximum daily exposure: 3 mgSource →
- Route: INTRAMUSCULAR; Dosage form: INJECTION; Maximum daily exposure: 1751 mgSource →
- Route: INTRAMUSCULAR; Dosage form: INJECTION, POWDER, FOR SOLUTION; Potency: 139.2 mgSource →
- Route: INTRAMUSCULAR; Dosage form: INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION; Maximum daily exposure: 1751 mgSource →
- Route: INTRAMUSCULAR; Dosage form: INJECTION, SUSPENSION; Maximum daily exposure: 36 mgSource →
- Route: INTRAMUSCULAR; Dosage form: INJECTION, SUSPENSION, EXTENDED RELEASE; Maximum daily exposure: 8 mgSource →
- Route: INTRAOCULAR; Dosage form: INSERT; Potency: 0.02 mgSource →
- Route: INTRASYNOVIAL; Dosage form: INJECTION, SUSPENSION; Maximum daily exposure: 3 mgSource →
- Route: INTRATHECAL; Dosage form: INJECTION, SOLUTION; Maximum daily exposure: 1 mgSource →
- Route: INTRAVENOUS; Dosage form: INJECTION; Maximum daily exposure: 381 mgSource →
- Route: INTRAVENOUS; Dosage form: INJECTION, EMULSION; Potency: 0.28 %w/vSource →
- Route: INTRAVENOUS; Dosage form: INJECTION, POWDER, FOR SOLUTION; Potency: 139.2 mgSource →
- Route: INTRAVENOUS; Dosage form: INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION; Maximum daily exposure: 1751 mgSource →
- Route: INTRAVENOUS; Dosage form: INJECTION, SOLUTION; Maximum daily exposure: 2460 mgSource →
- Route: INTRAVENOUS; Dosage form: LIQUID; Maximum daily exposure: 381 mgSource →
- Route: INTRAVENOUS; Dosage form: SOLUTION; Maximum daily exposure: 381 mgSource →
- Route: INTRAVESICAL; Dosage form: INJECTION, SOLUTION; Potency: 38.25 mgSource →
- Route: NASAL; Dosage form: SOLUTION; Potency: 5 mgSource →
- Route: NASAL; Dosage form: SPRAY; Maximum daily exposure: 1 mgSource →
- Route: NASAL; Dosage form: SPRAY, METERED; Maximum daily exposure: 7 mgSource →
- Route: OPHTHALMIC; Dosage form: SOLUTION; Potency: 1.21 %w/vSource →
- Route: OPHTHALMIC; Dosage form: SOLUTION/ DROPS; Potency: 1.4 %w/vSource →
- Route: OPHTHALMIC; Dosage form: SUSPENSION; Potency: NASource →
- Route: ORAL; Dosage form: CAPSULE; Potency: 40 mgSource →
- Route: ORAL; Dosage form: CAPSULE, DELAYED RELEASE; Maximum daily exposure: 43 mgSource →
- Route: ORAL; Dosage form: CAPSULE, EXTENDED RELEASE; Maximum daily exposure: 207 mgSource →
- Route: ORAL; Dosage form: FILM, SOLUBLE; Potency: 0.05 mgSource →
- Route: ORAL; Dosage form: SOLUTION; Maximum daily exposure: 140 mgSource →
- Route: ORAL; Dosage form: SUSPENSION; Maximum daily exposure: 66 mgSource →
- Route: ORAL; Dosage form: SYRUP; Maximum daily exposure: 70 mgSource →
- Route: ORAL; Dosage form: TABLET; Maximum daily exposure: 96 mgSource →
- Route: ORAL; Dosage form: TABLET, EXTENDED RELEASE; Maximum daily exposure: 210 mgSource →
- Route: ORAL; Dosage form: TABLET, FILM COATED; Potency: 0.01 mgSource →
- Route: ORAL; Dosage form: TABLET, FOR SUSPENSION; Maximum daily exposure: 60 mgSource →
- Route: ORAL; Dosage form: TROCHE; Potency: 28 mgSource →
- Route: SOFT TISSUE; Dosage form: INJECTION, SUSPENSION; Maximum daily exposure: 3 mgSource →
- Route: SUBCUTANEOUS; Dosage form: INJECTION; Maximum daily exposure: 20 mgSource →
- Route: SUBCUTANEOUS; Dosage form: INJECTION, SOLUTION; Potency: 0.11 %w/vSource →
- Route: SUBLINGUAL; Dosage form: FILM; Maximum daily exposure: 6 mgSource →
- + 8 more entries not shown
GLOBALJECFAEvaluated2 entries
- JECFA evaluation record.Source →
- JECFA evaluation record. Functional class: texturizer, thickener, acidity regulator, emulsifier.Source →
EUCosIngActiveListed in CosIng inventory for cosmetic use.
- Listed in CosIng inventory for cosmetic use.Source →
USEPAcommercial use observedEPA CPDat observed this chemical in 1204 composition records across product categories including Laboratory supplies, Cleaning and safety, Industrial products. EPA CPDat classifies this chemical for functional uses including Deodorizer, pH regulating agent, Corrosion inhibitor.
- EPA CPDat observed this chemical in 1204 composition records across product categories including Laboratory supplies, Cleaning and safety, Industrial products. EPA CPDat classifies this chemical for functional uses including Deodorizer, pH regulating agent, Corrosion inhibitor.Source →
USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 19 active drug products and 20 total products.
- FDA NDC lists this ingredient in 19 active drug products and 20 total products.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
- openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

Independent scientific assessments cited by the records we hold, with the year and link where the record gives one.

SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.
JECFA
Joint FAO/WHO Expert Committee on Food Additives
- JECFA evaluation record.
  Year not recorded · GLOBAL JECFA listing · Read the source →
- JECFA evaluation record. Functional class: texturizer, thickener, acidity regulator, emulsifier.
  Year not recorded · GLOBAL JECFA listing · Read the source →

Evidence & sources

No graded research studies for Sodium phosphate, dibasic, anhydrous yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

9 data sources

Where this comes from

CosIng
regulatory · updated 2026-09-23
Open →
EPA Chemical and Products Database
exposure · updated september 3, 2013
Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
Open →
FDA Inactive Ingredient Database
regulatory · updated 2026-01-09
Open →
FDA National Drug Code Directory
regulatory · updated 2028-12-31
Open →
FDA GSRS UNII
registry · updated 2026-02-26
Open →
WHO JECFA Database
regulatory · updated 2026-10-04
Open →
openFDA Substance
registry · updated 2026-05-24
Open →
PubChem Live Enrichment
chemistry · updated 2026-05-17
Open →

Reference links (1)

Openfda substance

codexalimentarius.net

Read →

Allergen profile

Canonical allergen markers detected on this ingredient. Each row is derived from the ingredient’s name or synonyms matching a known allergen class — useful when scanning a label for a specific allergy context.

MolluscsContains · Oral (ingested)
Source: chemindex_name_match

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.

Fragrance avoidance

Not a strong fit for fragrance avoidance because it carries Fragrance.

Avoid

The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.

Where it has been recorded

How often EPA CPDat has listed Sodium phosphate, dibasic, anhydrous in a product composition. These are source records, not Greenveil catalog products.

Source records

1,204

Named organisations

Laboratory suppliesCleaning and safetyIndustrial productsVehicleSpecialty occupational productsMedical/dental

Typical roles

AnticorrosiveBufferingFragranceTexturizer, thickener, acidity regulator, emulsifierChelating agentpH adjuster

See products using Sodium phosphate, dibasic, anhydrous →

Catalog

Found in these products

Their ingredient lists include Sodium phosphate, dibasic, anhydrous; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 269 →Find products without it →