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Proteinase from B. Subtilis

CAS 9001-93-8

Also registered as 20 other CAS numbers

9012-23-1 · 9040-76-0 · 80804-52-0 · 105913-13-1 · 116267-38-0 · 117278-03-2 · 117698-27-8 · 118390-80-0 · 118901-82-9 · 120038-39-3 · 120038-40-6 · 123779-18-0 · 124041-97-0 · 125498-72-8 · 125752-86-5 · 143404-30-2 · 143404-41-5 · 144906-30-9 · 609346-52-3 · 9001-92-7

Concern score

Not assessed — no hazard data yet.

Proteinase from B. Subtilis in plain language

What it is

On cosmetic ingredient lists it appears as “Protease”.

Also known as Protease · 537 Acidic protease · AKase IK · Actinase · Alcalase 2.5L-DX · Alcalase 2.5LDX

Show all 12 names

Alkalase 2.4L FG · proteolytic Enzymes · Proteinase · bacterial protease · endoproteinase · proteolytic enzyme

What it does

Used in cosmetics as a skin-conditioning agent.

  • Skin conditioning
  • Emulsifier
  • Flavouring
  • Conditioner
  • Cleaning agent
Is it a concern?
We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

Regulation

No restrictions found. Proteinase from B. Subtilis appears in these published regulatory listings.

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • Cleaning
  • Industrial
  • EUCosIngActiveListed in CosIng inventory for cosmetic use.
    • Listed in CosIng inventory for cosmetic use.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 447 composition records across product categories including Cleaning products and household care, Cleaning and safety, Laboratory supplies. EPA CPDat classifies this chemical for functional uses including Cleaning agent, Softener and conditioner, Chemical reaction regulator.
    • EPA CPDat observed this chemical in 447 composition records across product categories including Cleaning products and household care, Cleaning and safety, Laboratory supplies. EPA CPDat classifies this chemical for functional uses including Cleaning agent, Softener and conditioner, Chemical reaction regulator.Source →

Expert safety opinions

No expert opinion on file for Proteinase from B. Subtilis. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Proteinase from B. Subtilis yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

3 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EPA Chemical and Products Database

    exposure · updated october 15, 2019

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.

Where it has been recorded

How often EPA CPDat has listed Proteinase from B. Subtilis in a product composition. These are source records, not Greenveil catalog products.

Source records

447

Named organisations

6

Cleaning products and household careCleaning and safetyLaboratory suppliesPersonal care

Typical roles

Skin conditioningEmulsifierFlavouringConditionerCleaning agent
See products using Proteinase from B. Subtilis →

Catalog

Found in these products

Their ingredient lists include Proteinase from B. Subtilis; each product's own rating depends on its whole formula, so it is shown on the product page, not here.