beauty
cleaning
food
industrial

Ascorbyl palmitate

CAS 1330-84-3 · 40/100 · High conf.

Also registered as 8 other CAS numbers

57233-83-7 · 120398-58-5 · 162872-43-7 · 924964-24-9 · 948551-42-6 · 1184913-60-7 · 2095286-71-6 · 137-66-6

Concern score

40/100Moderate concern based on regulatory listings.

High confidence

Ascorbyl palmitate in plain language

What it is: Also known as 6-O-PALMITOYLASCORBIC acid · Ascorbyl monopalmitate · Cetyl ascorbate · E-304 · Ins NO.304 · INS-304
Show all 26 names
L-ascorbic acid 6-PALMITATE · L-ascorbic acid, 6-HEXADECANOATE · 6-Hexadecanoyl-L-ascorbic acid · 6-Monopalmitoyl-L-ascorbate · 6-O-Palmitoyl ascorbate · 6-O-Palmitoyl-L-ascorbic acid · 6-O-Palmitoylascorbinsaure · 6-Palmitate-L-ascorbic acid · 6-Palmitoylascorbic acid · Ascorboyl palmitate · Ascorbyl 6-hexadecanoate, L- · Ascorbyl 6-palmitate · Ascorbyl palmitate (VAN) · Ascorbylpalmitic acid · L-ascorbyl 6-palmitate · Ondascora · Palmitoyl L-ascorbic acid · Quicifal · ascorbic palmitate · l-ascorbyl palmitate
What it does: Used in cosmetics as an antioxidant and a fragrance ingredient.
Antioxidant
Fragrance
Preservative
Deodorant
Is it a concern?: Moderate concern: no hazard classifications on record. It is listed for cosmetic use in the EU.

Why it's flagged

EPA CPDat observed this chemical in 3409 composition records across product categories including Industrial products, Personal care, Construction.

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

No restrictions found. Ascorbyl palmitate appears in these published regulatory listings.

In marketed US drugs
Inactive ingredient in US drugs

Recorded in these product areas

Found in consumer products
Beauty
Cleaning
Pharma
Food
Industrial

USFDAinactive ingredient database6 entries — 3 administration routes
- Route: TOPICAL; Dosage form: SOLUTION; Potency: NASource →
- Route: TOPICAL; Dosage form: SYSTEM; Potency: 0.04 mgSource →
- Route: TOPICAL; Dosage form: CREAM; Potency: 0.02 %w/wSource →
- Route: RECTAL; Dosage form: SUPPOSITORY; Maximum daily exposure: 16 mgSource →
- Route: ORAL; Dosage form: TABLET; Potency: 7.14 mgSource →
- Route: ORAL; Dosage form: CAPSULE; Potency: 12 mgSource →
EUEFSAEFSA opinion3 entries
- Opinion on the re-evaluation of ascorbyl palmitate (E 304i) as a food additive in foods for infants below 16 weeks of age and the follow-up of its re-evaluation as a food additive for uses in foods for all population groups (EFSA FAF)Source →
- Scientific Opinion on the safety and efficacy of vitamin C (ascorbic acid, sodium ascorbate, calcium ascorbate, ascorbyl palmitate, sodium calcium ascorbyl phosphate and sodium ascorbyl phosphate) as a feed additive for all animal species based on a dossier submitted by DSM Nutritional Products Ltd (EFSA FEEDAP)Source →
- Scientific Opinion on the re-evaluation of ascorbyl palmitate (E 304(i)) and ascorbyl stearate (E 304(ii)) as food additives (EFSA ANS)Source →
EUCosIngActiveListed in CosIng inventory for cosmetic use.
- Listed in CosIng inventory for cosmetic use.Source →
GLOBALJECFA0-1.25 mg/kg bwJECFA evaluation lists ADI 0-1.25 mg/kg bw. Functional class: antioxidant.
- JECFA evaluation lists ADI 0-1.25 mg/kg bw. Functional class: antioxidant.Source →
USEPAcommercial use observedEPA CPDat observed this chemical in 3409 composition records across product categories including Industrial products, Personal care, Construction. EPA CPDat classifies this chemical for functional uses including Antioxidant, Deodorizer, Fragrance.
- EPA CPDat observed this chemical in 3409 composition records across product categories including Industrial products, Personal care, Construction. EPA CPDat classifies this chemical for functional uses including Antioxidant, Deodorizer, Fragrance.Source →
USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 1 active drug products and 6 total products.
- FDA NDC lists this ingredient in 1 active drug products and 6 total products.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
- openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

Independent scientific assessments cited by the records we hold, with the year and link where the record gives one.

SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.
EFSA
European Food Safety Authority
- Opinion on the re-evaluation of ascorbyl palmitate (E 304i) as a food additive in foods for infants below 16 weeks of age and the follow-up of its re-evaluation as a food additive for uses in foods for all population groups (EFSA FAF)
  2020 · EU EFSA listing · Read the source →
- Scientific Opinion on the safety and efficacy of vitamin C (ascorbic acid, sodium ascorbate, calcium ascorbate, ascorbyl palmitate, sodium calcium ascorbyl phosphate and sodium ascorbyl phosphate) as a feed additive for all animal species based on a dossier submitted by DSM Nutritional Products Ltd (EFSA FEEDAP)
  2013 · EU EFSA listing · Read the source →
- Scientific Opinion on the re-evaluation of ascorbyl palmitate (E 304(i)) and ascorbyl stearate (E 304(ii)) as food additives (EFSA ANS)
  2015 · EU EFSA listing · Read the source →
JECFA
Joint FAO/WHO Expert Committee on Food Additives
- JECFA evaluation lists ADI 0-1.25 mg/kg bw. Functional class: antioxidant.
  Year not recorded · GLOBAL JECFA listing · Read the source →

Evidence & sources

No graded research studies for Ascorbyl palmitate yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

10 data sources

Where this comes from

CosIng
regulatory · updated 2026-09-23
Open →
EFSA OpenFoodTox
regulatory · updated 2026-10-04
Open →
EPA Chemical and Products Database
exposure · updated may 3, 2019
Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
Open →
FDA Inactive Ingredient Database
regulatory · updated 2026-01-09
Open →
FDA National Drug Code Directory
regulatory · updated 2029-04-29
Open →
FDA GSRS UNII
registry · updated 2026-02-26
Open →
WHO JECFA Database
regulatory · updated 2026-10-04
Open →
openFDA Substance
registry · updated 2026-05-24
Open →
PubChem Live Enrichment
chemistry · updated 2026-05-17
Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

Not a strong fit for fragrance avoidance because it carries Fragrance.

Avoid

The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.

Where it has been recorded

How often EPA CPDat has listed Ascorbyl palmitate in a product composition. These are source records, not Greenveil catalog products.

Source records

3,409

Named organisations

Industrial productsPersonal careConstructionBatteriesRaw materialsFood and drug

Typical roles

AntioxidantFragrancePreservativeDeodorant

See products using Ascorbyl palmitate →

Catalog

Found in these products

Their ingredient lists include Ascorbyl palmitate; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 515 →Find products without it →

Co-occurrence

Often appears with

Ingredients that frequently appear alongside Ascorbyl palmitate in the catalog.