What does .alpha.-tocopherol, dl- do?

Used in food as an antioxidant.

Is .alpha.-tocopherol, dl- safe?

Moderate concern: no hazard classifications on record.

beauty
cleaning
food
industrial

.alpha.-tocopherol, dl-

E307 · CAS 10191-41-0 · 40/100 · High conf.

Also registered as 8 other CAS numbers

18920-62-2 · 113085-06-6 · 1411583-24-8 · 364-50-1 · 4072-33-7 · 16826-11-2 · 25094-97-7 · 181591-70-8

.alpha.-tocopherol, dl- chemical structure

Concern score

40/100Moderate concern based on regulatory listings.

High confidence

.alpha.-tocopherol, dl- in plain language

What it is: Also known as Dl-alpha tocopherol · All-rac-alpha-tocopherol · Dl-.alpha.-tocopherol · (+/-)-alpha-Tocopherol · DL-alpha-Tocopherol · alpha-Tocopherol
Show all 28 names
(+)-alpha-tocopherol · DL-5,7,8-TRIMETHYLTOCOL · DL-ALPHA-TOCOPHEROL(307C) · Ephanyl · Irganox e 210 · Rac-.alpha.-tocopherol · Ronotec df 120 · Rrr-alpha-tocopherol · Uvinul 2000AO · Vitamin e dl-alpha · (+/-)-α-Tocopherol · Alpha-tocopherol, dl- · DL-α-Tocopherol · E-307C · Ec 233-466-0 · Ins NO.307C · INS-307C · J24.789H · UNII-7QWA1RIO01 · tocopherol · tocopherol acetate · tocopheryl acetate
What it does: Used in food as an antioxidant.
Antioxidant
Preservative
Fragrance
Conditioner
Is it a concern?: Moderate concern: no hazard classifications on record.

As a food additive

E-number

E307

Used in food as

Antioxidant

EU safety status

EFSA re-evaluated E307 in 2015: no safety concern at authorised uses.

It never counts as an additive of concern in a product’s food rating.

EFSA Journal 2015;13(9):4247 — Scientific Opinion on the re-evaluation of tocopherol-rich extract (E 306), α-tocopherol (E 307), γ-tocopherol (E 308) and δ-tocopherol (E 309) as food additives

Why it's flagged

EPA CPDat observed this chemical in 29 composition records across product categories including Industrial products, Personal care.

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

No restrictions found. .alpha.-tocopherol, dl- appears in these published regulatory listings.

In marketed US drugs
Inactive ingredient in US drugs

Recorded in these product areas

Found in consumer products
Beauty
Cleaning
Industrial

USFDAinactive ingredient database11 entries — 4 administration routes
- Route: ORAL; Dosage form: SUSPENSION; Potency: 0.01 mg/1mlSource →
- Route: ORAL; Dosage form: TABLET; Potency: 0.12 mgSource →
- Route: ORAL; Dosage form: TABLET, CHEWABLE; Potency: 0.02 mgSource →
- Route: TOPICAL; Dosage form: AEROSOL, FOAM; Potency: NASource →
- Route: TOPICAL; Dosage form: OINTMENT; Potency: NASource →
- Route: TRANSDERMAL; Dosage form: SYSTEM; Potency: 0.14 mgSource →
- Route: ORAL; Dosage form: SOLUTION; Maximum daily exposure: 4 mgSource →
- Route: ORAL; Dosage form: POWDER, FOR SUSPENSION; Potency: NASource →
- Route: ORAL; Dosage form: CAPSULE; Maximum daily exposure: 90 mgSource →
- Route: INTRAVENOUS; Dosage form: SOLUTION, CONCENTRATE; Potency: 0.08 %w/vSource →
- Route: INTRAVENOUS; Dosage form: INJECTION, EMULSION; Maximum daily exposure: 178 mgSource →
EUEFSAEFSA opinion3 entries
- Scientific Opinion on the re-evaluation of tocopherol-rich extract (E 306), alpha-tocopherol (E 307), gamma-tocopherol (E 308) and delta-tocopherol (E 309) as food additives (EFSA ANS)Source →
- Scientific Opinion on the safety and efficacy of synthetic alpha-tocopherol for all animal species (EFSA FEEDAP)Source →
- Scientific Opinion on Dietary Reference Values for vitamin E as alpha-tocopherol (EFSA NDA)Source →
GLOBALJECFA0.15-2 mg/kg bwJECFA evaluation lists ADI 0.15-2 mg/kg bw. Functional class: antioxidant.
- JECFA evaluation lists ADI 0.15-2 mg/kg bw. Functional class: antioxidant.Source →
GLOBALJECFAEvaluatedJECFA evaluation record.
- JECFA evaluation record.Source →
USEPAcommercial use observedEPA CPDat observed this chemical in 29 composition records across product categories including Industrial products, Personal care. EPA CPDat classifies this chemical for functional uses including Antioxidant, Softener and conditioner, Fragrance.
- EPA CPDat observed this chemical in 29 composition records across product categories including Industrial products, Personal care. EPA CPDat classifies this chemical for functional uses including Antioxidant, Softener and conditioner, Fragrance.Source →
USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 7 active drug products and 7 total products.
- FDA NDC lists this ingredient in 7 active drug products and 7 total products.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
- openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

Independent scientific assessments cited by the records we hold, with the year and link where the record gives one.

JECFA
Joint FAO/WHO Expert Committee on Food Additives
- JECFA evaluation lists ADI 0.15-2 mg/kg bw. Functional class: antioxidant.
  Year not recorded · GLOBAL JECFA listing · Read the source →
- JECFA evaluation record.
  Year not recorded · GLOBAL JECFA listing · Read the source →
EFSA
European Food Safety Authority
- Scientific Opinion on the re-evaluation of tocopherol-rich extract (E 306), alpha-tocopherol (E 307), gamma-tocopherol (E 308) and delta-tocopherol (E 309) as food additives (EFSA ANS)
  2015 · EU EFSA listing · Read the source →
- Scientific Opinion on the safety and efficacy of synthetic alpha-tocopherol for all animal species (EFSA FEEDAP)
  2012 · EU EFSA listing · Read the source →
- Scientific Opinion on Dietary Reference Values for vitamin E as alpha-tocopherol (EFSA NDA)
  2015 · EU EFSA listing · Read the source →

Evidence & sources

No graded research studies for .alpha.-tocopherol, dl- yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

9 data sources

Where this comes from

EFSA OpenFoodTox
regulatory · updated 2026-10-04
Open →
EPA Chemical and Products Database
exposure · updated september 4, 2014
Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
Open →
FDA Inactive Ingredient Database
regulatory · updated 2026-01-09
Open →
FDA National Drug Code Directory
regulatory · updated 2027-12-31
Open →
FDA GSRS UNII
registry · updated 2026-02-26
Open →
WHO JECFA Database
regulatory · updated 2026-10-04
Open →
openFDA Substance
registry · updated 2026-05-24
Open →
PubChem Live Enrichment
chemistry · updated 2026-05-17
Open →

Reference links (4)

Openfda substance

codexalimentarius.net

Read →

Openfda substance

fao.org

Read →

Openfda substance

codexalimentarius.net

Read →

Openfda substance

nikkajiweb.jst.go.jp

Read →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

Not a strong fit for fragrance avoidance because it carries Fragrance.

Avoid

The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.

Where it has been recorded

How often EPA CPDat has listed .alpha.-tocopherol, dl- in a product composition. These are source records, not Greenveil catalog products.

Source records

Named organisations

Industrial productsPersonal care

Typical roles

AntioxidantPreservativeFragranceConditioner

See products using .alpha.-tocopherol, dl- →

Catalog

Found in these products

Their ingredient lists include .alpha.-tocopherol, dl-; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 317 →Find products without it →

Co-occurrence

Often appears with

Ingredients that frequently appear alongside .alpha.-tocopherol, dl- in the catalog.