- beauty
- cleaning
- food
- industrial
D-alpha-Tocopheryl acetate
CAS 54-22-8 · 20/100 · High conf.
Also registered as 5 other CAS numbers
1406-70-8 · 12741-00-3 · 26243-95-8 · 58-95-7 · 7695-91-2
Concern score
20/100Minor concern based on regulatory listings.
High confidence
D-alpha-Tocopheryl acetate in plain language
On cosmetic ingredient lists it appears as “Tocopheryl acetate”.
Also known as Tocopheryl acetate · .alpha.-tocopherol acetate · D-alpha tocoferil acetate · Rrr-alpha-tocopheryl acetate · Rrr-alpha-tocopheryl acetate concentrate · D-alpha tocopheryl acetate
Show all 45 names
.alpha.-tocopherol acetate, d- · Alpha-Tocopherol Acetate · (+)-alfa-tocopherol acetate · Alpha-tocopheryl acetate, d- · D-.alpha.-tocopheryl acetate · Tocopheryl acetate, .alpha., d- · (+)-α-Tocopherol acetate · (+)-α-Tocopheryl acetate · (2R,4'R,8'R)-α-Tocopherol acetate · (2R,4'R,8'R)-α-Tocopheryl acetate · (R,R,R)-α-Tocopheryl acetate · .alpha.-tocopherol acetate. d- · Alfacol · Combinal E · Contopheron · Copherol 1250 · Covitol 1100 · Covitol 1360 · D-Vitamin E acetate · D-alpha-Tocopherol acetate · Ecofrol · Econ · Endo E Dompe · Ephynal acetate · Erevit · Evipherol · Gevex · J24.807J · Juvela · Tocopherex · Tocopherol acetate · Tocophrin · Tofaxin · Tokoferol acetate · Vitamin E · Vitamin E acetate · Vitamin Ealpha acetate · tocopheryl (vitamin e) acetate · tocopheryl acetate (vitamin e acetate)
Used in cosmetics as an antioxidant and a skin-conditioning agent.
- Antioxidant
- Skin conditioning
- Preservative
- Humectant
- Fragrance
- Flavouring
- Minor concern: no hazard classifications on record. It is listed for cosmetic use in the EU.
Why it's flagged
EPA CPDat observed this chemical in 14638 composition records across product categories including Personal care, Cleaning and safety, Construction.
The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.
Regulation
No restrictions found. D-alpha-Tocopheryl acetate appears in these published regulatory listings.
- Found in consumer products
- Beauty
- Cleaning
- Pharma
- Food
- Industrial
EUCosIngActiveListed in CosIng inventory for cosmetic use.
- Listed in CosIng inventory for cosmetic use.Source →
USEPAcommercial use observedEPA CPDat observed this chemical in 14638 composition records across product categories including Personal care, Cleaning and safety, Construction. EPA CPDat classifies this chemical for functional uses including Preservative, Antioxidant, Softener and conditioner.
- EPA CPDat observed this chemical in 14638 composition records across product categories including Personal care, Cleaning and safety, Construction. EPA CPDat classifies this chemical for functional uses including Preservative, Antioxidant, Softener and conditioner.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
- openFDA substance registry classifies this ingredient as chemical.Source →
Expert safety opinions
Independent scientific assessments cited by the records we hold, with the year and link where the record gives one.
SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.
EFSA
European Food Safety Authority
Safety assessment of the substance alpha-tocopherol acetate for use in food contact materials (EFSA CEF)
2016 · EU EFSA listing · Read the source →
Scientific Opinion on the safety and efficacy of vitamin E as a feed additive for all animal species (EFSA FEEDAP)
2010 · EU EFSA listing · Read the source →
Evidence & sources
No graded research studies for D-alpha-Tocopheryl acetate yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.
Where this comes from
- Open →
CosIng
regulatory · updated 2026-09-23
- Open →
EFSA OpenFoodTox
regulatory · updated 2026-10-04
- Open →
EPA Chemical and Products Database
exposure · updated september 9, 2014
- Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
- Open →
FDA GSRS UNII
registry · updated 2026-02-26
- Open →
openFDA Substance
registry · updated 2026-05-24
- Open →
PubChem Live Enrichment
chemistry · updated 2026-05-17
Reference links (1)
Suitability
Context-specific fit derived from published classifications and the current ingredient evidence profile.
Food use
Food-use source coverage is present in the current record.
The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.
Fragrance avoidance
Not a strong fit for fragrance avoidance because it carries Fragrance.
The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.
Where it has been recorded
How often EPA CPDat has listed D-alpha-Tocopheryl acetate in a product composition. These are source records, not Greenveil catalog products.
Source records
14,638
Named organisations
6
Personal careCleaning and safetyConstructionBatteriesFood and drugCleaning products and household care
Typical roles
AntioxidantSkin conditioningPreservativeHumectantFragranceFlavouring
Found in these products
Their ingredient lists include D-alpha-Tocopheryl acetate; each product's own rating depends on its whole formula, so it is shown on the product page, not here.
- Nivea softNivéa · Cosmetic Products
- Cream pure urea 10%Deliplus · Body
- NottregonaNeutrogena · Open Beauty Facts
- body lotionNivea · Beurre De Cocoa
- ToallitasDodot
- pantine pro-vpantine · Open Beauty Facts
- Crème pour la peau ClassicCien · Body
- lidl crème de soin hydratantecien · Non Food Products
- Lait HydratantHyderma · Non Food Products
- Botanical flowChamps de Provence
- Tratamiento Mais CachosSkala Expert, Skala · Haarmasker
- Anti manchasDeliplus
- Crema oliveDeliplus,Mercadona · Fats
- Chargement…Non Food Products
- Mixed Fruit Fruit SnacksWelch's · Snacks
- sun protection
- Barritas con proteínas sabor coco y chocolateEnervit Sport · Snacks
- head and shoulders classicHead & Shoulders · Non Food Products
- Kids spray solaireCien Sun · Open Beauty Facts
- crema solar facialDeliplus
- Crema corporal nutritiva con aceite de argánDeliplus · Non Food Products
- Neutrogena Lipcare Stick Norwegian FormulaNeutrogena · Face
- Crema hidratanteDeliplus · Open Beauty Facts
- HimalayaHimalaya · Cosmetic Products
Often appears with
Ingredients that frequently appear alongside D-alpha-Tocopheryl acetate in the catalog.