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GREENVEIL

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.alpha.-tocopherol

E307 · CAS 1406-18-4 · 0/100 · High conf.

Concern score

0/100Low concern — well-established and permitted without restriction (FDA GRAS; CIR safe as used; EU food additive; EU CosIng).
High confidence

.alpha.-tocopherol in plain language

What it is

Also known as Vitamin e · Alpha tocopherol · Vitamin e oil · Alpha-tocopherols · Aquasol e · Envirose 100

Show all 9 names

Unspecified form vitamin e · J203.513H · Vitamin e (as alpha tocopherol)

What it does

We don't have a plain-language description for .alpha.-tocopherol yet.

Is it a concern?
Low concern: no hazard classifications on record.

As a food additive

E-number
E307
Used in food as
  • Antioxidant
EU safety status

EFSA re-evaluated E307 in 2015: no safety concern at authorised uses.

It never counts as an additive of concern in a product’s food rating.

  • EFSA Journal 2015;13(9):4247 — Scientific Opinion on the re-evaluation of tocopherol-rich extract (E 306), α-tocopherol (E 307), γ-tocopherol (E 308) and δ-tocopherol (E 309) as food additives

Why it's flagged

Route: BUCCAL; Dosage form: FILM, SOLUBLE; Potency: 0.07 mg

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

No restrictions found. .alpha.-tocopherol appears in these published regulatory listings.

  • In marketed US drugs
  • Inactive ingredient in US drugs
  • USFDAinactive ingredient database10 entries — 4 administration routes
    • Route: BUCCAL; Dosage form: FILM, SOLUBLE; Potency: 0.07 mgSource →
    • Route: INTRAVENOUS; Dosage form: INJECTION, POWDER, FOR SUSPENSION; Potency: 0.64 mgSource →
    • Route: ORAL; Dosage form: CAPSULE; Maximum daily exposure: 16 mgSource →
    • Route: ORAL; Dosage form: SOLUTION; Potency: 1.05 mg/1mlSource →
    • Route: ORAL; Dosage form: TABLET; Maximum daily exposure: 2 mgSource →
    • Route: ORAL; Dosage form: TABLET, CHEWABLE; Potency: 0.1 mgSource →
    • Route: ORAL; Dosage form: TABLET, EXTENDED RELEASE; Maximum daily exposure: 4 mgSource →
    • Route: ORAL; Dosage form: TABLET, FILM COATED; Maximum daily exposure: 246 mgSource →
    • Route: TOPICAL; Dosage form: OINTMENT; Potency: NASource →
    • Route: TOPICAL; Dosage form: SYSTEM; Potency: 0.1 mgSource →
  • USFDAlisted in openFDA substance2 entries
    • openFDA substance registry classifies this ingredient as mixture.Source →
    • openFDA substance registry classifies this ingredient as concept.Source →
  • USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 18 active drug products and 20 total products.
    • FDA NDC lists this ingredient in 18 active drug products and 20 total products.Source →

Evidence & sources

No graded research studies for .alpha.-tocopherol yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

4 data sources

Where this comes from

  • FDA Inactive Ingredient Database

    regulatory · updated 2026-01-09

    Open →

  • FDA National Drug Code Directory

    regulatory · updated 2029-04-29

    Open →

  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →

  • openFDA Substance

    registry · updated 2026-05-24

    Open →
Reference links (3)
Openfda substance

en.wikipedia.org

Read →
Openfda substance

drugoffice.gov.hk

Read →
Openfda substance

nikkajiweb.jst.go.jp

Read →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often FDA National Drug Code directory has listed .alpha.-tocopherol in a product composition. These are source records, not Greenveil catalog products.

Source records

20

See products using .alpha.-tocopherol →

Catalog

Found in these products

Their ingredient lists include .alpha.-tocopherol; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 1000+ →Find products without it →

Co-occurrence

Often appears with

Ingredients that frequently appear alongside .alpha.-tocopherol in the catalog.